null

SMILES: C(Nc1nc(nc2ccsc12)N1CCCCC1)c1ccccc1

InChI Key: InChIKey=WTRJSVKSGFVZPG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50471846   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Homo sapiens (Human))	BDBM50471846 (CHEMBL434822) Show SMILES C(Nc1nc(nc2ccsc12)N1CCCCC1)c1ccccc1 Show InChI InChI=1S/C18H20N4S/c1-3-7-14(8-4-1)13-19-17-16-15(9-12-23-16)20-18(21-17)22-10-5-2-6-11-22/h1,3-4,7-9,12H,2,5-6,10-11,13H2,(H,19,20,21)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Increased cAMP accumulation in isoprenaline-induced guinea pig eosinophils				J Med Chem 41: 4021-35 (1998) Article DOI: 10.1021/jm981012m BindingDB Entry DOI: 10.7270/Q2TM7DV3
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50471846 (CHEMBL434822) Show SMILES C(Nc1nc(nc2ccsc12)N1CCCCC1)c1ccccc1 Show InChI InChI=1S/C18H20N4S/c1-3-7-14(8-4-1)13-19-17-16-15(9-12-23-16)20-18(21-17)22-10-5-2-6-11-22/h1,3-4,7-9,12H,2,5-6,10-11,13H2,(H,19,20,21)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibitory activity against cGMP inhibited Phosphodiesterase 3, isolated from guinea pig ventricular tissue				J Med Chem 41: 4021-35 (1998) Article DOI: 10.1021/jm981012m BindingDB Entry DOI: 10.7270/Q2TM7DV3
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Homo sapiens (Human))	BDBM50471846 (CHEMBL434822) Show SMILES C(Nc1nc(nc2ccsc12)N1CCCCC1)c1ccccc1 Show InChI InChI=1S/C18H20N4S/c1-3-7-14(8-4-1)13-19-17-16-15(9-12-23-16)20-18(21-17)22-10-5-2-6-11-22/h1,3-4,7-9,12H,2,5-6,10-11,13H2,(H,19,20,21)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Inhibitory activity against phosphodiesterase 4 isolated from guinea pig ventricular tissue				J Med Chem 41: 4021-35 (1998) Article DOI: 10.1021/jm981012m BindingDB Entry DOI: 10.7270/Q2TM7DV3
					More data for this Ligand-Target Pair