null

SMILES: CN(CCOc1ccc(CC(Nc2ccccc2C(=O)c2cccc3ccccc23)C(O)=O)cc1)c1nc2ccccc2o1

InChI Key: InChIKey=XKFGSRFZGHVKHK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50472052   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50472052 (CHEMBL145958) Show SMILES CN(CCOc1ccc(CC(Nc2ccccc2C(=O)c2cccc3ccccc23)C(O)=O)cc1)c1nc2ccccc2o1 Show InChI InChI=1S/C36H31N3O5/c1-39(36-38-31-15-6-7-16-33(31)44-36)21-22-43-26-19-17-24(18-20-26)23-32(35(41)42)37-30-14-5-4-12-29(30)34(40)28-13-8-10-25-9-2-3-11-27(25)28/h2-20,32,37H,21-23H2,1H3,(H,41,42)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Wellcome Research and Development Curated by ChEMBL					Assay Description The compound was tested in vitro for inhibiting the 50% binding of Peroxisome proliferator activated receptor gamma				J Med Chem 41: 5055-69 (1998) Article DOI: 10.1021/jm980414r BindingDB Entry DOI: 10.7270/Q2DB84MJ
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50472052 (CHEMBL145958) Show SMILES CN(CCOc1ccc(CC(Nc2ccccc2C(=O)c2cccc3ccccc23)C(O)=O)cc1)c1nc2ccccc2o1 Show InChI InChI=1S/C36H31N3O5/c1-39(36-38-31-15-6-7-16-33(31)44-36)21-22-43-26-19-17-24(18-20-26)23-32(35(41)42)37-30-14-5-4-12-29(30)34(40)28-13-8-10-25-9-2-3-11-27(25)28/h2-20,32,37H,21-23H2,1H3,(H,41,42)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.70	n/a	n/a	n/a	n/a
Glaxo Wellcome Research and Development Curated by ChEMBL					Assay Description -log concentration required to induce 50% maximum lipogenic activity against Peroxisome proliferator activated receptor gamma				J Med Chem 41: 5055-69 (1998) Article DOI: 10.1021/jm980414r BindingDB Entry DOI: 10.7270/Q2DB84MJ
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50472052 (CHEMBL145958) Show SMILES CN(CCOc1ccc(CC(Nc2ccccc2C(=O)c2cccc3ccccc23)C(O)=O)cc1)c1nc2ccccc2o1 Show InChI InChI=1S/C36H31N3O5/c1-39(36-38-31-15-6-7-16-33(31)44-36)21-22-43-26-19-17-24(18-20-26)23-32(35(41)42)37-30-14-5-4-12-29(30)34(40)28-13-8-10-25-9-2-3-11-27(25)28/h2-20,32,37H,21-23H2,1H3,(H,41,42)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	85	n/a	n/a	n/a	n/a
Glaxo Wellcome Research and Development Curated by ChEMBL					Assay Description The compound was tested functionally in vitro for inducing 50% of the maximum alkaline phosphatase activity (Transactivation) against Peroxisome prol...				J Med Chem 41: 5055-69 (1998) Article DOI: 10.1021/jm980414r BindingDB Entry DOI: 10.7270/Q2DB84MJ
					More data for this Ligand-Target Pair