BDBM50472270 CHEMBL294794

SMILES: CC(C)OP(=O)(COCCn1c(Br)nc2c(O)nc(N)nc12)OC(C)C

InChI Key: InChIKey=AQENQMWWXQEOFK-UHFFFAOYSA-N

Data: 6 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50472270   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thymidine kinase (Human herpesvirus 3)	BDBM50472270 (CHEMBL294794) Show SMILES CC(C)OP(=O)(COCCn1c(Br)nc2c(O)nc(N)nc12)OC(C)C Show InChI InChI=1S/C14H23BrN5O5P/c1-8(2)24-26(22,25-9(3)4)7-23-6-5-20-11-10(17-13(20)15)12(21)19-14(16)18-11/h8-9H,5-7H2,1-4H3,(H3,16,18,19,21)	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.10E+5	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibitory activity against varicella zoster virus thymidine kinase (VZV TK+) OKA strain				J Med Chem 42: 2064-86 (1999) Article DOI: 10.1021/jm9811256 BindingDB Entry DOI: 10.7270/Q2CF9ST6
					More data for this Ligand-Target Pair
Thymidine kinase (Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)	BDBM50472270 (CHEMBL294794) Show SMILES CC(C)OP(=O)(COCCn1c(Br)nc2c(O)nc(N)nc12)OC(C)C Show InChI InChI=1S/C14H23BrN5O5P/c1-8(2)24-26(22,25-9(3)4)7-23-6-5-20-11-10(17-13(20)15)12(21)19-14(16)18-11/h8-9H,5-7H2,1-4H3,(H3,16,18,19,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.30E+5	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibitory activity against herpes simplex virus type 1 (HSV-1) thymidine kinase (TK) VMW 1837 strain				J Med Chem 42: 2064-86 (1999) Article DOI: 10.1021/jm9811256 BindingDB Entry DOI: 10.7270/Q2CF9ST6
					More data for this Ligand-Target Pair
Thymidine kinase (Human herpesvirus 3)	BDBM50472270 (CHEMBL294794) Show SMILES CC(C)OP(=O)(COCCn1c(Br)nc2c(O)nc(N)nc12)OC(C)C Show InChI InChI=1S/C14H23BrN5O5P/c1-8(2)24-26(22,25-9(3)4)7-23-6-5-20-11-10(17-13(20)15)12(21)19-14(16)18-11/h8-9H,5-7H2,1-4H3,(H3,16,18,19,21)	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.10E+5	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of varicella zoster virus thymidine kinase (VZV TK+) YS/R strain				J Med Chem 42: 2064-86 (1999) Article DOI: 10.1021/jm9811256 BindingDB Entry DOI: 10.7270/Q2CF9ST6
					More data for this Ligand-Target Pair
Thymidine kinase (Human herpesvirus 3)	BDBM50472270 (CHEMBL294794) Show SMILES CC(C)OP(=O)(COCCn1c(Br)nc2c(O)nc(N)nc12)OC(C)C Show InChI InChI=1S/C14H23BrN5O5P/c1-8(2)24-26(22,25-9(3)4)7-23-6-5-20-11-10(17-13(20)15)12(21)19-14(16)18-11/h8-9H,5-7H2,1-4H3,(H3,16,18,19,21)	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.10E+5	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibitory activity against varicella zoster virus thymidine kinase (VZV TK-) 07/1 strain				J Med Chem 42: 2064-86 (1999) Article DOI: 10.1021/jm9811256 BindingDB Entry DOI: 10.7270/Q2CF9ST6
					More data for this Ligand-Target Pair
Thymidine kinase (Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)	BDBM50472270 (CHEMBL294794) Show SMILES CC(C)OP(=O)(COCCn1c(Br)nc2c(O)nc(N)nc12)OC(C)C Show InChI InChI=1S/C14H23BrN5O5P/c1-8(2)24-26(22,25-9(3)4)7-23-6-5-20-11-10(17-13(20)15)12(21)19-14(16)18-11/h8-9H,5-7H2,1-4H3,(H3,16,18,19,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>8.84E+5	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibition of herpes simplex virus type 1 thymidine kinase (HSV-1 TK-) B2006 strain				J Med Chem 42: 2064-86 (1999) Article DOI: 10.1021/jm9811256 BindingDB Entry DOI: 10.7270/Q2CF9ST6
					More data for this Ligand-Target Pair
Thymidine kinase (Human herpesvirus 3)	BDBM50472270 (CHEMBL294794) Show SMILES CC(C)OP(=O)(COCCn1c(Br)nc2c(O)nc(N)nc12)OC(C)C Show InChI InChI=1S/C14H23BrN5O5P/c1-8(2)24-26(22,25-9(3)4)7-23-6-5-20-11-10(17-13(20)15)12(21)19-14(16)18-11/h8-9H,5-7H2,1-4H3,(H3,16,18,19,21)	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.10E+5	n/a	n/a	n/a	n/a
Academy of Sciences of the Czech Republic Curated by ChEMBL					Assay Description Inhibitory activity against varicella zoster virus thymidine kinase (VZV TK+) YS strain				J Med Chem 42: 2064-86 (1999) Article DOI: 10.1021/jm9811256 BindingDB Entry DOI: 10.7270/Q2CF9ST6
					More data for this Ligand-Target Pair