null
SMILES: CC(C)(C)c1cc(\C=C2/CCN(c3ccc(Cl)cc3)S2(=O)=O)cc(c1O)C(C)(C)C
InChI Key: InChIKey=KYVQOTMVUACBCO-CPNJWEJPSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin G/H synthase 1/2 (RAT) | BDBM50472624![]() (CHEMBL62439) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | <1 | n/a | n/a | n/a | n/a | n/a | n/a |
Shionogi & Co., Ltd. Curated by ChEMBL | Assay Description In vitro inhibitory effect on production of prostaglandin E2 (PGE2) in rat synovial cells. | J Med Chem 43: 2040-8 (2000) Article DOI: 10.1021/jm9906015 BindingDB Entry DOI: 10.7270/Q2H134R8 | |||||||||||
More data for this Ligand-Target Pair |