BDBM50472718 CHEMBL72567

SMILES: C[C@@](O)(C(=O)Nc1ccc(cc1Cl)S(=O)(=O)N1CCC(N)C1)C(F)(F)F

InChI Key: InChIKey=RAPGJWJWLNLLJV-AZMWARKLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50472718   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Pyruvate dehydrogenase kinase (Homo sapiens (Human))	BDBM50472718 (CHEMBL72567) Show SMILES C[C@@](O)(C(=O)Nc1ccc(cc1Cl)S(=O)(=O)N1CCC(N)C1)C(F)(F)F Show InChI InChI=1S/C14H17ClF3N3O4S/c1-13(23,14(16,17)18)12(22)20-11-3-2-9(6-10(11)15)26(24,25)21-5-4-8(19)7-21/h2-3,6,8,23H,4-5,7,19H2,1H3,(H,20,22)/t8?,13-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of porcine pyruvate dehydrogenase kinase (PDHK)in a primary enzymatic assay				J Med Chem 43: 2248-57 (2000) Article DOI: 10.1021/jm0000923 BindingDB Entry DOI: 10.7270/Q2C82D1Z
					More data for this Ligand-Target Pair