BDBM50472814 CHEMBL309318

SMILES: C[C@@](O)(C(=O)N1CCN(CC1)c1ccccc1)C(F)(F)F

InChI Key: InChIKey=LBPILVSVEUTBMN-CYBMUJFWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50472814   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial (Rattus norvegicus)	BDBM50472814 (CHEMBL309318) Show SMILES C[C@@](O)(C(=O)N1CCN(CC1)c1ccccc1)C(F)(F)F Show InChI InChI=1S/C14H17F3N2O2/c1-13(21,14(15,16)17)12(20)19-9-7-18(8-10-19)11-5-3-2-4-6-11/h2-6,21H,7-10H2,1H3/t13-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity tested against Pyruvate Dehydrogenase Kinase (PDHK) receptor from rats.				J Med Chem 43: 236-49 (2000) Article DOI: 10.1021/jm990358+ BindingDB Entry DOI: 10.7270/Q2B85BVQ
					More data for this Ligand-Target Pair