BDBM50473224 CHEMBL296660

SMILES: CCC[C@H]1C2CCC(C2)[C@H]1NC1=NCCO1

InChI Key: InChIKey=IPQYPIRIGUBUAF-MMVSWEMESA-N

Data: 3 KI  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50473224   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50473224 (CHEMBL296660) Show SMILES CCC[C@H]1C2CCC(C2)[C@H]1NC1=NCCO1 |t:13,THB:10:9:8:6.5| Show InChI InChI=1S/C13H22N2O/c1-2-3-11-9-4-5-10(8-9)12(11)15-13-14-6-7-16-13/h9-12H,2-8H2,1H3,(H,14,15)/t9?,10?,11-,12+/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibitory constant against human Alpha-2A adrenergic receptor expressed in LM(tk-) cells using [3H]rauwolscine				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Adrenergic receptor (Homo sapiens (Human))	BDBM50473224 (CHEMBL296660) Show SMILES CCC[C@H]1C2CCC(C2)[C@H]1NC1=NCCO1 |t:13,THB:10:9:8:6.5| Show InChI InChI=1S/C13H22N2O/c1-2-3-11-9-4-5-10(8-9)12(11)15-13-14-6-7-16-13/h9-12H,2-8H2,1H3,(H,14,15)/t9?,10?,11-,12+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibitory constant against human Alpha-2B adrenergic receptor expressed in Y-1 cells using [3H]rauwolscine				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Adrenergic receptor (Homo sapiens (Human))	BDBM50473224 (CHEMBL296660) Show SMILES CCC[C@H]1C2CCC(C2)[C@H]1NC1=NCCO1 |t:13,THB:10:9:8:6.5| Show InChI InChI=1S/C13H22N2O/c1-2-3-11-9-4-5-10(8-9)12(11)15-13-14-6-7-16-13/h9-12H,2-8H2,1H3,(H,14,15)/t9?,10?,11-,12+/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	123	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Inhibitory constant, using [3H]rauwolscine in LM(tk-) cells stably transfected with cloned human Alpha-2C adrenergic receptor				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Adrenergic receptor (Homo sapiens (Human))	BDBM50473224 (CHEMBL296660) Show SMILES CCC[C@H]1C2CCC(C2)[C@H]1NC1=NCCO1 |t:13,THB:10:9:8:6.5| Show InChI InChI=1S/C13H22N2O/c1-2-3-11-9-4-5-10(8-9)12(11)15-13-14-6-7-16-13/h9-12H,2-8H2,1H3,(H,14,15)/t9?,10?,11-,12+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	562	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Alpha-2B adrenergic receptor agonism measured as ability to inhibit forskolin-stimulated synthesis of cAMP				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Adrenergic receptor (Homo sapiens (Human))	BDBM50473224 (CHEMBL296660) Show SMILES CCC[C@H]1C2CCC(C2)[C@H]1NC1=NCCO1 |t:13,THB:10:9:8:6.5| Show InChI InChI=1S/C13H22N2O/c1-2-3-11-9-4-5-10(8-9)12(11)15-13-14-6-7-16-13/h9-12H,2-8H2,1H3,(H,14,15)/t9?,10?,11-,12+/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	21	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Alpha2c receptor agonism measured as ability to inhibit forskolin-stimulated synthesis of cAMP				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50473224 (CHEMBL296660) Show SMILES CCC[C@H]1C2CCC(C2)[C@H]1NC1=NCCO1 |t:13,THB:10:9:8:6.5| Show InChI InChI=1S/C13H22N2O/c1-2-3-11-9-4-5-10(8-9)12(11)15-13-14-6-7-16-13/h9-12H,2-8H2,1H3,(H,14,15)/t9?,10?,11-,12+/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Alpha-2A adrenergic receptor agonism measured as ability to inhibit forskolin-stimulated synthesis of cAMP				J Med Chem 43: 1699-704 (2000) Article DOI: 10.1021/jm9905256 BindingDB Entry DOI: 10.7270/Q2D221C4
					More data for this Ligand-Target Pair