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SMILES: COc1ccc(cc1OC)C1=NN(CC#N)C(=O)C2CCCCC12

InChI Key: InChIKey=WJHOHNMVCLXSFV-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50473689   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D


(Homo sapiens (Human))		BDBM50473689
PNG
(CHEMBL316171)
Show SMILES COc1ccc(cc1OC)C1=NN(CC#N)C(=O)C2CCCCC12 |t:11|
Show InChI InChI=1S/C18H21N3O3/c1-23-15-8-7-12(11-16(15)24-2)17-13-5-3-4-6-14(13)18(22)21(20-17)10-9-19/h7-8,11,13-14H,3-6,10H2,1-2H3
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 63n/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory concentration against phosphodiesterase 4 (PDE4) in cytosol of human neutrophils

J Med Chem 45: 2520-5 (2002)


Article DOI: 10.1021/jm0110340
BindingDB Entry DOI: 10.7270/Q2862K56
More data for this
Ligand-Target Pair