BDBM50474245 CHEMBL320279
SMILES: NC[C@H]1O[C@H](C=C1)c1c[nH]cn1
InChI Key: InChIKey=DCDBUDNURLZBED-POYBYMJQSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50474245 (CHEMBL320279) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.15E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Osaka University Curated by ChEMBL | Assay Description Histamine H3 receptor competition binding using [3H]Na-methylhistamine | J Med Chem 46: 3162-5 (2003) Article DOI: 10.1021/jm0300025 BindingDB Entry DOI: 10.7270/Q24B343F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine receptor (H3 and H4) (Homo sapiens (Human)) | BDBM50474245 (CHEMBL320279) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.19E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Osaka University Curated by ChEMBL | Assay Description Histamine H4 receptor competition binding using [3H]Na-methylhistamine | J Med Chem 46: 3162-5 (2003) Article DOI: 10.1021/jm0300025 BindingDB Entry DOI: 10.7270/Q24B343F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Homo sapiens (Human)) | BDBM50474245 (CHEMBL320279) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 2.69E+4 | n/a | n/a | n/a | n/a |
Osaka University Curated by ChEMBL | Assay Description Inhibition of the forskolin-stimulated cAMP production in SK-N-MC cells expressing human Histamine H3 receptor | J Med Chem 46: 3162-5 (2003) Article DOI: 10.1021/jm0300025 BindingDB Entry DOI: 10.7270/Q24B343F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine receptor (H3 and H4) (Homo sapiens (Human)) | BDBM50474245 (CHEMBL320279) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 4.07E+4 | n/a | n/a | n/a | n/a |
Osaka University Curated by ChEMBL | Assay Description Inhibition of the forskolin-stimulated cAMP production in SK-N-MC cells expressing human Histamine H4 receptor | J Med Chem 46: 3162-5 (2003) Article DOI: 10.1021/jm0300025 BindingDB Entry DOI: 10.7270/Q24B343F | |||||||||||
More data for this Ligand-Target Pair |