BDBM50474339 CHEMBL141236

SMILES: ONC(=O)\C=C\c1ccc(CNCCc2cn(CC3CC3)c3ccccc23)cc1

InChI Key: InChIKey=FAGBOEVMPXWLID-VAWYXSNFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50474339   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1/2/3/4/5/6/7/8/9/11/Polyamine deacetylase HDAC10 (Homo sapiens (Human))	BDBM50474339 (CHEMBL141236) Show SMILES ONC(=O)\C=C\c1ccc(CNCCc2cn(CC3CC3)c3ccccc23)cc1 Show InChI InChI=1S/C24H27N3O2/c28-24(26-29)12-11-18-5-7-19(8-6-18)15-25-14-13-21-17-27(16-20-9-10-20)23-4-2-1-3-22(21)23/h1-8,11-12,17,20,25,29H,9-10,13-16H2,(H,26,28)/b12-11+	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibitory activity against histone deacetylase (HDAC) enzyme obtained from H1299 human lung carcinoma cell lysates				J Med Chem 46: 4609-24 (2003) Article DOI: 10.1021/jm030235w BindingDB Entry DOI: 10.7270/Q2736TP0
					More data for this Ligand-Target Pair