BDBM50474937 CHEMBL191460
SMILES: OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CN(C)CCN(Cc1ccc(cc1)-c1ccc(CNCCc2ccccc2)cc1)C(=O)CCC1CCCC1
InChI Key: InChIKey=SEQAMPXQRKYYQF-UHFFFAOYSA-N
Data: 15 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM50474937 (CHEMBL191460) | KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 6.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Binding affinity towards human 5-hydroxytryptamine receptor 5A expressed in CHO cells using the radioligand [3H]LSD | Bioorg Med Chem Lett 15: 4014-8 (2005) Article DOI: 10.1016/j.bmcl.2005.06.024 BindingDB Entry DOI: 10.7270/Q25141Z0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adrenergic receptor (Homo sapiens (Human)) | BDBM50474937 (CHEMBL191460) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 316 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Binding affinity towards human alpha-1B-adrenergic receptor expressed in CHO cells using the radioligand [3H]prazosin | Bioorg Med Chem Lett 15: 4014-8 (2005) Article DOI: 10.1016/j.bmcl.2005.06.024 BindingDB Entry DOI: 10.7270/Q25141Z0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin (5-HT) receptor (Homo sapiens (Human)) | BDBM50474937 (CHEMBL191460) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 316 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Binding affinity towards human 5-hydroxytryptamine receptor 1B expressed in CHO cells using the radioligand [3H]5-HT | Bioorg Med Chem Lett 15: 4014-8 (2005) Article DOI: 10.1016/j.bmcl.2005.06.024 BindingDB Entry DOI: 10.7270/Q25141Z0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50474937 (CHEMBL191460) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 398 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Binding affinity towards human 5-hydroxytryptamine receptor 2C expressed in HEK 293 cells using the radioligand [3H]mesulergine | Bioorg Med Chem Lett 15: 4014-8 (2005) Article DOI: 10.1016/j.bmcl.2005.06.024 BindingDB Entry DOI: 10.7270/Q25141Z0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin (5-HT) receptor (Homo sapiens (Human)) | BDBM50474937 (CHEMBL191460) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 398 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Binding affinity towards human 5-hydroxytryptamine receptor 1D expressed in CHO cells using the radioligand [3H]5-HT | Bioorg Med Chem Lett 15: 4014-8 (2005) Article DOI: 10.1016/j.bmcl.2005.06.024 BindingDB Entry DOI: 10.7270/Q25141Z0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50474937 (CHEMBL191460) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 501 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Binding affinity towards human 5-hydroxytryptamine receptor 1A expressed in HEK 293 cells using the radioligand [3H]8-OH-DPAT | Bioorg Med Chem Lett 15: 4014-8 (2005) Article DOI: 10.1016/j.bmcl.2005.06.024 BindingDB Entry DOI: 10.7270/Q25141Z0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50474937 (CHEMBL191460) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 631 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Binding affinity towards human dopamine receptor D3 expressed in CHO cells using the radioligand [125I]iodosulpiride | Bioorg Med Chem Lett 15: 4014-8 (2005) Article DOI: 10.1016/j.bmcl.2005.06.024 BindingDB Entry DOI: 10.7270/Q25141Z0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(4) dopamine receptor (Homo sapiens (Human)) | BDBM50474937 (CHEMBL191460) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 794 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Binding affinity towards human dopamine receptor D4 expressed in CHO cells using the radioligand [125I]iodosulpiride | Bioorg Med Chem Lett 15: 4014-8 (2005) Article DOI: 10.1016/j.bmcl.2005.06.024 BindingDB Entry DOI: 10.7270/Q25141Z0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50474937 (CHEMBL191460) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 794 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Binding affinity towards human 5-hydroxytryptamine receptor 2A expressed in HEK 293 cells using the radioligand [3H]ketanserin | Bioorg Med Chem Lett 15: 4014-8 (2005) Article DOI: 10.1016/j.bmcl.2005.06.024 BindingDB Entry DOI: 10.7270/Q25141Z0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2B (Homo sapiens (Human)) | BDBM50474937 (CHEMBL191460) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Binding affinity towards human 5-hydroxytryptamine receptor 2B expressed in HEK 293 cells using the radioligand [3H]5-HT | Bioorg Med Chem Lett 15: 4014-8 (2005) Article DOI: 10.1016/j.bmcl.2005.06.024 BindingDB Entry DOI: 10.7270/Q25141Z0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50474937 (CHEMBL191460) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Binding affinity towards human dopamine receptor D2 expressed in CHO cells using the radioligand [125I]iodosulpiride | Bioorg Med Chem Lett 15: 4014-8 (2005) Article DOI: 10.1016/j.bmcl.2005.06.024 BindingDB Entry DOI: 10.7270/Q25141Z0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 6 (Homo sapiens (Human)) | BDBM50474937 (CHEMBL191460) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Binding affinity towards human 5-hydroxytryptamine receptor 6 expressed in HeLa cells using the radioligand [3H]LSD | Bioorg Med Chem Lett 15: 4014-8 (2005) Article DOI: 10.1016/j.bmcl.2005.06.024 BindingDB Entry DOI: 10.7270/Q25141Z0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50474937 (CHEMBL191460) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Binding affinity towards human 5-hydroxytryptamine receptor 7 expressed in HEK 293 cells using the radioligand [3H]5-CT | Bioorg Med Chem Lett 15: 4014-8 (2005) Article DOI: 10.1016/j.bmcl.2005.06.024 BindingDB Entry DOI: 10.7270/Q25141Z0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin (5-HT) receptor (Homo sapiens (Human)) | BDBM50474937 (CHEMBL191460) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Binding affinity towards human 5-hydroxytryptamine receptor 1E expressed in HEK 293 cells using the radioligand [3H]5-HT | Bioorg Med Chem Lett 15: 4014-8 (2005) Article DOI: 10.1016/j.bmcl.2005.06.024 BindingDB Entry DOI: 10.7270/Q25141Z0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin (5-HT) receptor (Homo sapiens (Human)) | BDBM50474937 (CHEMBL191460) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Binding affinity towards human 5-hydroxytryptamine receptor 1F expressed in HEK 293 cells using the radioligand [3H]5-HT | Bioorg Med Chem Lett 15: 4014-8 (2005) Article DOI: 10.1016/j.bmcl.2005.06.024 BindingDB Entry DOI: 10.7270/Q25141Z0 | |||||||||||
More data for this Ligand-Target Pair |