BDBM50479338 CHEMBL513910

SMILES: OC(COc1ccc2c(cc(=O)oc2c1)-c1ccccc1)CN1CCNCC1

InChI Key: InChIKey=DPPQNKKMNSPLRU-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50479338   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM50479338 (CHEMBL513910) Show SMILES OC(COc1ccc2c(cc(=O)oc2c1)-c1ccccc1)CN1CCNCC1 Show InChI InChI=1S/C22H24N2O4/c25-17(14-24-10-8-23-9-11-24)15-27-18-6-7-19-20(16-4-2-1-3-5-16)13-22(26)28-21(19)12-18/h1-7,12-13,17,23,25H,8-11,14-15H2	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.65E+4	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Antagonist activity at histamine H1 receptor in guinea pig ileum assessed as inhibition of histamine-induced contractions at 0.5 mg/ml				Bioorg Med Chem 16: 9009-17 (2008) Article DOI: 10.1016/j.bmc.2008.08.039 BindingDB Entry DOI: 10.7270/Q2PR7ZSZ
					More data for this Ligand-Target Pair
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM50479338 (CHEMBL513910) Show SMILES OC(COc1ccc2c(cc(=O)oc2c1)-c1ccccc1)CN1CCNCC1 Show InChI InChI=1S/C22H24N2O4/c25-17(14-24-10-8-23-9-11-24)15-27-18-6-7-19-20(16-4-2-1-3-5-16)13-22(26)28-21(19)12-18/h1-7,12-13,17,23,25H,8-11,14-15H2	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.26E+4	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Antagonist activity at histamine H1 receptor in guinea pig ileum assessed as inhibition of histamine-induced contractions at 1.0 mg/ml				Bioorg Med Chem 16: 9009-17 (2008) Article DOI: 10.1016/j.bmc.2008.08.039 BindingDB Entry DOI: 10.7270/Q2PR7ZSZ
					More data for this Ligand-Target Pair
Histamine H1 receptor (Cavia porcellus (domestic guinea pig))	BDBM50479338 (CHEMBL513910) Show SMILES OC(COc1ccc2c(cc(=O)oc2c1)-c1ccccc1)CN1CCNCC1 Show InChI InChI=1S/C22H24N2O4/c25-17(14-24-10-8-23-9-11-24)15-27-18-6-7-19-20(16-4-2-1-3-5-16)13-22(26)28-21(19)12-18/h1-7,12-13,17,23,25H,8-11,14-15H2	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.52E+4	n/a	n/a	n/a	n/a
Cairo University Curated by ChEMBL					Assay Description Antagonist activity at histamine H1 receptor in guinea pig ileum assessed as inhibition of histamine-induced contractions at 0.1 mg/ml				Bioorg Med Chem 16: 9009-17 (2008) Article DOI: 10.1016/j.bmc.2008.08.039 BindingDB Entry DOI: 10.7270/Q2PR7ZSZ
					More data for this Ligand-Target Pair