BDBM50479450 CHEMBL451806

SMILES: CC(C)[C@H](CO)Nc1nc(Nc2cccc(c2)-c2ccccc2)c2ncn(C(C)C)c2n1

InChI Key: InChIKey=MXEURNZDWSQFOE-NRFANRHFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50479450   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 (Sus scrofa)	BDBM50479450 (CHEMBL451806) Show SMILES CC(C)[C@H](CO)Nc1nc(Nc2cccc(c2)-c2ccccc2)c2ncn(C(C)C)c2n1 |r| Show InChI InChI=1S/C25H30N6O/c1-16(2)21(14-32)28-25-29-23(22-24(30-25)31(15-26-22)17(3)4)27-20-12-8-11-19(13-20)18-9-6-5-7-10-18/h5-13,15-17,21,32H,14H2,1-4H3,(H2,27,28,29,30)/t21-/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universite Paris-Descartes Curated by ChEMBL					Assay Description Inhibition of pig brain GSK3alpha/beta				J Med Chem 51: 5229-42 (2008) Article DOI: 10.1021/jm800109e BindingDB Entry DOI: 10.7270/Q2DB84PF
					More data for this Ligand-Target Pair