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SMILES: O=C(Nc1ccccc1)OCc1cn2ncnc2s1

InChI Key: InChIKey=SONPUYUNALZLLZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50483167   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM50483167
PNG
(CHEMBL1630073)
Show SMILES O=C(Nc1ccccc1)OCc1cn2ncnc2s1
Show InChI InChI=1S/C12H10N4O2S/c17-12(15-9-4-2-1-3-5-9)18-7-10-6-16-11(19-10)13-8-14-16/h1-6,8H,7H2,(H,15,17)
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PC cid
PC sid
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Article
PubMed
n/an/a<3.16E+4n/an/an/an/an/an/a



Medicines Research Centre

Curated by ChEMBL


Assay Description
Antagonist activity at human mGluR5 expressed in CHO cells assessed as doxycycline induced calcium mobilization

Bioorg Med Chem Lett 20: 7521-4 (2010)


Article DOI: 10.1016/j.bmcl.2010.09.120
BindingDB Entry DOI: 10.7270/Q2KH0R5D
More data for this
Ligand-Target Pair