BDBM50484400 CHEMBL1916075

SMILES: Cl.CCOc1cc(ccc1OC)C(=CC#N)c1ccc(OC)c(OC(=O)CN)c1

InChI Key: InChIKey=NQDQONQTHUPPNR-CXUHLZMHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50484400   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 4 (Homo sapiens (Human))	BDBM50484400 (CHEMBL1916075) Show SMILES Cl.CCOc1cc(ccc1OC)C(=CC#N)c1ccc(OC)c(OC(=O)CN)c1 Show InChI InChI=1S/C21H22N2O5/c1-4-27-19-11-14(5-7-17(19)25-2)16(9-10-22)15-6-8-18(26-3)20(12-15)28-21(24)13-23/h5-9,11-12H,4,13,23H2,1-3H3/b16-9+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of human PDE4 expressed in U937 cells using [3H]cAMP as substrate after 30 mins				Bioorg Med Chem 19: 6356-74 (2011) Article DOI: 10.1016/j.bmc.2011.08.068 BindingDB Entry DOI: 10.7270/Q2Z60RXK
					More data for this Ligand-Target Pair