BDBM50484436 CHEMBL1915831

SMILES: COc1ccc(cc1)C(=CC#N)c1ccc(OC)c(OC)c1

InChI Key: InChIKey=MXRZRMQHGDCNEC-YBEGLDIGSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50484436   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 4 (Homo sapiens (Human))	BDBM50484436 (CHEMBL1915831) Show SMILES COc1ccc(cc1)C(=CC#N)c1ccc(OC)c(OC)c1 Show InChI InChI=1S/C18H17NO3/c1-20-15-7-4-13(5-8-15)16(10-11-19)14-6-9-17(21-2)18(12-14)22-3/h4-10,12H,1-3H3/b16-10-	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of human PDE4 expressed in U937 cells using [3H]cAMP as substrate after 30 mins				Bioorg Med Chem 19: 6356-74 (2011) Article DOI: 10.1016/j.bmc.2011.08.068 BindingDB Entry DOI: 10.7270/Q2Z60RXK
					More data for this Ligand-Target Pair