null

SMILES:

InChI Key: InChIKey=OCYCJENTLYSSKA-FZJCYGCTSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50484880   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrase (Human immunodeficiency virus 1)	BDBM50484880 (CHEMBL2012010) Show SMILES Show InChI InChI=1S/C140H167Br4N36O76P11S/c1-55-33-170(134(197)163-117(55)184)91-23-70(84(237-91)44-227-262(211,212)251-73-26-94(173-36-58(4)120(187)166-137(173)200)235-81(73)41-224-257(8,204)247-71-24-92(171-34-56(2)118(185)164-135(171)198)238-85(71)45-228-263(213,214)255-78-31-100(179-53-152-107-115(179)157-131(147)161-126(107)193)243-89(78)49-230-261(209,210)249-69-22-98(234-80(69)40-181)177-51-150-105-113(177)155-129(145)159-124(105)191)246-258(9,205)225-42-82-74(27-95(236-82)174-37-59(5)121(188)167-138(174)201)252-265(217,218)232-48-88-76(29-97(241-88)176-39-61(7)123(190)169-140(176)203)253-266(219,220)233-50-90-79(32-101(244-90)180-54-153-108-116(180)158-132(148)162-127(108)194)256-264(215,216)229-46-86-72(25-93(239-86)172-35-57(3)119(186)165-136(172)199)248-259(10,206)226-43-83-77(30-99(242-83)178-52-151-106-114(178)156-130(146)160-125(106)192)254-267(221,222)231-47-87-75(28-96(240-87)175-38-60(6)122(189)168-139(175)202)250-260(207,208)223-18-14-12-11-13-17-149-133(268)154-62-15-16-63(64(19-62)128(195)196)102-65-20-67(141)109(182)103(143)111(65)245-112-66(102)21-68(142)110(183)104(112)144/h15-16,19-21,33-39,51-54,69-101,181-182H,11-14,17-18,22-32,40-50H2,1-10H3,(H,195,196)(H,207,208)(H,209,210)(H,211,212)(H,213,214)(H,215,216)(H,217,218)(H,219,220)(H,221,222)(H2,149,154,268)(H,163,184,197)(H,164,185,198)(H,165,186,199)(H,166,187,200)(H,167,188,201)(H,168,189,202)(H,169,190,203)(H3,145,155,159,191)(H3,146,156,160,192)(H3,147,157,161,193)(H3,148,158,162,194)/t69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80+,81+,82+,83+,84+,85+,86+,87+,88+,89+,90+,91+,92+,93+,94+,95+,96+,97+,98+,99+,100+,101+,257?,258?,259?/m0/s1	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Lomonosov Moscow State University Curated by ChEMBL					Assay Description Inhibition of Human immunodeficiency virus 1 integrase 3'-processing activity expressed in Escherichia coli using 21-mer DNA and Mg2+ after 2 hrs by ...				ACS Med Chem Lett 2: 532-7 (2011) Article DOI: 10.1021/ml200066k BindingDB Entry DOI: 10.7270/Q2Z03C00
					More data for this Ligand-Target Pair