BDBM50485276 CHEMBL233375

SMILES: COc1ccc(\C=C2/SC(=O)NC2=O)cc1O

InChI Key: InChIKey=MHRJJGJJVMGLRQ-UITAMQMPSA-N

Data: 2 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50485276   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosinase (Agaricus bisporus (Common mushroom))	BDBM50485276 (CHEMBL233375) Show SMILES COc1ccc(\C=C2/SC(=O)NC2=O)cc1O Show InChI InChI=1S/C11H9NO4S/c1-16-8-3-2-6(4-7(8)13)5-9-10(14)12-11(15)17-9/h2-5,13H,1H3,(H,12,14,15)/b9-5-	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pusan National University Curated by ChEMBL					Assay Description Competitive inhibition of mushroom tyrosinase using L-tyrosine as substrate at 1.25 uM by Line-Weaver-Burk plot analysis				Eur J Med Chem 49: 245-52 (2012) Article DOI: 10.1016/j.ejmech.2012.01.019 BindingDB Entry DOI: 10.7270/Q2DV1NR2
					More data for this Ligand-Target Pair
Tyrosinase (Agaricus bisporus (Common mushroom))	BDBM50485276 (CHEMBL233375) Show SMILES COc1ccc(\C=C2/SC(=O)NC2=O)cc1O Show InChI InChI=1S/C11H9NO4S/c1-16-8-3-2-6(4-7(8)13)5-9-10(14)12-11(15)17-9/h2-5,13H,1H3,(H,12,14,15)/b9-5-	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	1.38E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pusan National University Curated by ChEMBL					Assay Description Competitive inhibition of mushroom tyrosinase using L-tyrosine as substrate at 20 uM by Line-Weaver-Burk plot analysis				Eur J Med Chem 49: 245-52 (2012) Article DOI: 10.1016/j.ejmech.2012.01.019 BindingDB Entry DOI: 10.7270/Q2DV1NR2
					More data for this Ligand-Target Pair
Tyrosinase (Agaricus bisporus (Common mushroom))	BDBM50485276 (CHEMBL233375) Show SMILES COc1ccc(\C=C2/SC(=O)NC2=O)cc1O Show InChI InChI=1S/C11H9NO4S/c1-16-8-3-2-6(4-7(8)13)5-9-10(14)12-11(15)17-9/h2-5,13H,1H3,(H,12,14,15)/b9-5-	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.87E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pusan National University Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase activity using L-tyrosine as substrate after 30 mins by spectrophotometric analysis				Eur J Med Chem 49: 245-52 (2012) Article DOI: 10.1016/j.ejmech.2012.01.019 BindingDB Entry DOI: 10.7270/Q2DV1NR2
					More data for this Ligand-Target Pair