null

SMILES: CCC[C@H](O)Nc1nc(Nc2ccc(cc2)-c2ncccn2)c2ncn(C(C)C)c2n1

InChI Key: InChIKey=PBTNYNHOVGFGNO-KRWDZBQOSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50488803   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM50488803 (CHEMBL2295948) Show SMILES CCC[C@H](O)Nc1nc(Nc2ccc(cc2)-c2ncccn2)c2ncn(C(C)C)c2n1 |r| Show InChI InChI=1S/C22H26N8O/c1-4-6-17(31)27-22-28-20(18-21(29-22)30(13-25-18)14(2)3)26-16-9-7-15(8-10-16)19-23-11-5-12-24-19/h5,7-14,17,31H,4,6H2,1-3H3,(H2,26,27,28,29)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Homo sapiens (human) recombinant GST-tagged DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ and [gamma33P]ATP as substrate af...				Citation and Details Article DOI: 10.1007/s00044-012-0334-1 BindingDB Entry DOI: 10.7270/Q2ZP490F
					More data for this Ligand-Target Pair
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50488803 (CHEMBL2295948) Show SMILES CCC[C@H](O)Nc1nc(Nc2ccc(cc2)-c2ncccn2)c2ncn(C(C)C)c2n1 |r| Show InChI InChI=1S/C22H26N8O/c1-4-6-17(31)27-22-28-20(18-21(29-22)30(13-25-18)14(2)3)26-16-9-7-15(8-10-16)19-23-11-5-12-24-19/h5,7-14,17,31H,4,6H2,1-3H3,(H2,26,27,28,29)/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant CDK2/cyclin A using histone H1 and [gamma33P]ATP as substrate after 30 min by scintillation counting				Citation and Details Article DOI: 10.1007/s00044-012-0334-1 BindingDB Entry DOI: 10.7270/Q2ZP490F
					More data for this Ligand-Target Pair
Casein kinase 1, delta tv1 (Sus scrofa)	BDBM50488803 (CHEMBL2295948) Show SMILES CCC[C@H](O)Nc1nc(Nc2ccc(cc2)-c2ncccn2)c2ncn(C(C)C)c2n1 |r| Show InChI InChI=1S/C22H26N8O/c1-4-6-17(31)27-22-28-20(18-21(29-22)30(13-25-18)14(2)3)26-16-9-7-15(8-10-16)19-23-11-5-12-24-19/h5,7-14,17,31H,4,6H2,1-3H3,(H2,26,27,28,29)/t17-/m0/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Sus scrofa (pig) casein kinase 1delta/epsilon isolated from brain using RRKHAAIGpSAYSITA and [gamma33P]ATP as substrate after 30 min by...				Citation and Details Article DOI: 10.1007/s00044-012-0334-1 BindingDB Entry DOI: 10.7270/Q2ZP490F
					More data for this Ligand-Target Pair
G2/mitotic-specific cyclin-B (Asterina pectinifera)	BDBM50488803 (CHEMBL2295948) Show SMILES CCC[C@H](O)Nc1nc(Nc2ccc(cc2)-c2ncccn2)c2ncn(C(C)C)c2n1 |r| Show InChI InChI=1S/C22H26N8O/c1-4-6-17(31)27-22-28-20(18-21(29-22)30(13-25-18)14(2)3)26-16-9-7-15(8-10-16)19-23-11-5-12-24-19/h5,7-14,17,31H,4,6H2,1-3H3,(H2,26,27,28,29)/t17-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Asteroidea (starfish) Cyclin-dependent kinase 1/cyclin B isolated from oocyte using histone H1 and [gamma33P]ATP as substrate after 30 ...				Citation and Details Article DOI: 10.1007/s00044-012-0334-1 BindingDB Entry DOI: 10.7270/Q2ZP490F
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta/[Tau protein] kinase (Sus scrofa)	BDBM50488803 (CHEMBL2295948) Show SMILES CCC[C@H](O)Nc1nc(Nc2ccc(cc2)-c2ncccn2)c2ncn(C(C)C)c2n1 |r| Show InChI InChI=1S/C22H26N8O/c1-4-6-17(31)27-22-28-20(18-21(29-22)30(13-25-18)14(2)3)26-16-9-7-15(8-10-16)19-23-11-5-12-24-19/h5,7-14,17,31H,4,6H2,1-3H3,(H2,26,27,28,29)/t17-/m0/s1	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Sus scrofa (pig) glycogen synthase kinase 3alpha/beta isolated from brain using YRRAAVPPSPSLSRHSSPHQpSEDEEE and [gamma33P]ATP as substr...				Citation and Details Article DOI: 10.1007/s00044-012-0334-1 BindingDB Entry DOI: 10.7270/Q2ZP490F
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50488803 (CHEMBL2295948) Show SMILES CCC[C@H](O)Nc1nc(Nc2ccc(cc2)-c2ncccn2)c2ncn(C(C)C)c2n1 |r| Show InChI InChI=1S/C22H26N8O/c1-4-6-17(31)27-22-28-20(18-21(29-22)30(13-25-18)14(2)3)26-16-9-7-15(8-10-16)19-23-11-5-12-24-19/h5,7-14,17,31H,4,6H2,1-3H3,(H2,26,27,28,29)/t17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 and [gamma33P]ATP as substrate after 30 min by scintillation counting				Citation and Details Article DOI: 10.1007/s00044-012-0334-1 BindingDB Entry DOI: 10.7270/Q2ZP490F
					More data for this Ligand-Target Pair