BDBM50491653 CHEMBL2387136

SMILES: CCC(CC)c1nn(CCO)c2c1N=C(CNC2=O)c1ccccc1

InChI Key: InChIKey=WDFOZMDHGRGPRF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50491653   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Homo sapiens phosphodiesterase 2A (PDE2A) (Homo sapiens (Human))	BDBM50491653 (CHEMBL2387136) Show SMILES CCC(CC)c1nn(CCO)c2c1N=C(CNC2=O)c1ccccc1 |c:14| Show InChI InChI=1S/C19H24N4O2/c1-3-13(4-2)16-17-18(23(22-16)10-11-24)19(25)20-12-15(21-17)14-8-6-5-7-9-14/h5-9,13,24H,3-4,10-12H2,1-2H3,(H,20,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of PDE2 (unknown origin)				Bioorg Med Chem Lett 23: 3438-42 (2013) Article DOI: 10.1016/j.bmcl.2013.03.072 BindingDB Entry DOI: 10.7270/Q2MP5665
					More data for this Ligand-Target Pair
Phosphodiesterase 4 (Homo sapiens (Human))	BDBM50491653 (CHEMBL2387136) Show SMILES CCC(CC)c1nn(CCO)c2c1N=C(CNC2=O)c1ccccc1 |c:14| Show InChI InChI=1S/C19H24N4O2/c1-3-13(4-2)16-17-18(23(22-16)10-11-24)19(25)20-12-15(21-17)14-8-6-5-7-9-14/h5-9,13,24H,3-4,10-12H2,1-2H3,(H,20,25)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of PDE4 (unknown origin)				Bioorg Med Chem Lett 23: 3438-42 (2013) Article DOI: 10.1016/j.bmcl.2013.03.072 BindingDB Entry DOI: 10.7270/Q2MP5665
					More data for this Ligand-Target Pair