BDBM50491679 CHEMBL2387430

SMILES: COc1ccc(cc1-c1cnc(OC)nc1)C1=Nc2c(nn(CCO)c2C(=O)NC1)C(C)(C)C

InChI Key: InChIKey=DCQBHFJFGDDQBX-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50491679   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Homo sapiens phosphodiesterase 2A (PDE2A) (Homo sapiens (Human))	BDBM50491679 (CHEMBL2387430) Show SMILES COc1ccc(cc1-c1cnc(OC)nc1)C1=Nc2c(nn(CCO)c2C(=O)NC1)C(C)(C)C |t:18| Show InChI InChI=1S/C24H28N6O4/c1-24(2,3)21-19-20(30(29-21)8-9-31)22(32)25-13-17(28-19)14-6-7-18(33-4)16(10-14)15-11-26-23(34-5)27-12-15/h6-7,10-12,31H,8-9,13H2,1-5H3,(H,25,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of PDE2 catalytic domain (unknown origin)				Bioorg Med Chem Lett 23: 3443-7 (2013) Article DOI: 10.1016/j.bmcl.2013.03.082 BindingDB Entry DOI: 10.7270/Q2C53PR1
					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50491679 (CHEMBL2387430) Show SMILES COc1ccc(cc1-c1cnc(OC)nc1)C1=Nc2c(nn(CCO)c2C(=O)NC1)C(C)(C)C |t:18| Show InChI InChI=1S/C24H28N6O4/c1-24(2,3)21-19-20(30(29-21)8-9-31)22(32)25-13-17(28-19)14-6-7-18(33-4)16(10-14)15-11-26-23(34-5)27-12-15/h6-7,10-12,31H,8-9,13H2,1-5H3,(H,25,32)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	562	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of PDE4B catalytic domain (unknown origin)				Bioorg Med Chem Lett 23: 3443-7 (2013) Article DOI: 10.1016/j.bmcl.2013.03.082 BindingDB Entry DOI: 10.7270/Q2C53PR1
					More data for this Ligand-Target Pair