BDBM50491698 CHEMBL2387426

SMILES: COc1ccc(cc1-c1cnc(nc1)N1CCOCC1)C1=Nc2c(nn(CCO)c2C(=O)NC1)C(C)(C)C

InChI Key: InChIKey=XABGTSAIKICGRS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50491698   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Homo sapiens phosphodiesterase 2A (PDE2A) (Homo sapiens (Human))	BDBM50491698 (CHEMBL2387426) Show SMILES COc1ccc(cc1-c1cnc(nc1)N1CCOCC1)C1=Nc2c(nn(CCO)c2C(=O)NC1)C(C)(C)C |t:23| Show InChI InChI=1S/C27H33N7O4/c1-27(2,3)24-22-23(34(32-24)7-10-35)25(36)28-16-20(31-22)17-5-6-21(37-4)19(13-17)18-14-29-26(30-15-18)33-8-11-38-12-9-33/h5-6,13-15,35H,7-12,16H2,1-4H3,(H,28,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of PDE2 catalytic domain (unknown origin)				Bioorg Med Chem Lett 23: 3443-7 (2013) Article DOI: 10.1016/j.bmcl.2013.03.082 BindingDB Entry DOI: 10.7270/Q2C53PR1
					More data for this Ligand-Target Pair
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50491698 (CHEMBL2387426) Show SMILES COc1ccc(cc1-c1cnc(nc1)N1CCOCC1)C1=Nc2c(nn(CCO)c2C(=O)NC1)C(C)(C)C |t:23| Show InChI InChI=1S/C27H33N7O4/c1-27(2,3)24-22-23(34(32-24)7-10-35)25(36)28-16-20(31-22)17-5-6-21(37-4)19(13-17)18-14-29-26(30-15-18)33-8-11-38-12-9-33/h5-6,13-15,35H,7-12,16H2,1-4H3,(H,28,36)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	265	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of PDE4B catalytic domain (unknown origin)				Bioorg Med Chem Lett 23: 3443-7 (2013) Article DOI: 10.1016/j.bmcl.2013.03.082 BindingDB Entry DOI: 10.7270/Q2C53PR1
					More data for this Ligand-Target Pair