BDBM50493366 CHEMBL2425476

SMILES: ONC(=O)CC(O)c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=IBFNZPDYLZCKOS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50493366   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM50493366 (CHEMBL2425476) Show SMILES ONC(=O)CC(O)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C10H10F3NO3/c11-10(12,13)7-3-1-6(2-4-7)8(15)5-9(16)14-17/h1-4,8,15,17H,5H2,(H,14,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.89E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jishou University Curated by ChEMBL					Assay Description Inhibition of urease extracted from Helicobacter pylori ATCC 43504 assessed as ammonia production preincubated for 1.5 hrs by indophenol-based method				Eur J Med Chem 68: 212-21 (2013) Article DOI: 10.1016/j.ejmech.2013.07.047 BindingDB Entry DOI: 10.7270/Q28G8PNR
					More data for this Ligand-Target Pair