BDBM50494254 CHEMBL3087487

SMILES: COc1cccc2c1COc1cc(Nc3ccc(F)cc3N)ccc1C2=O

InChI Key: InChIKey=DSOQXAWKLQXARN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50494254   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50494254 (CHEMBL3087487) Show SMILES COc1cccc2c1COc1cc(Nc3ccc(F)cc3N)ccc1C2=O Show InChI InChI=1S/C21H17FN2O3/c1-26-19-4-2-3-14-16(19)11-27-20-10-13(6-7-15(20)21(14)25)24-18-8-5-12(22)9-17(18)23/h2-10,24H,11,23H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-University T£bingen Curated by ChEMBL					Assay Description Competitive inhibition of p38alpha MAP kinase (unknown origin) in presence of 100 uM ATP				J Med Chem 56: 8561-78 (2013) Article DOI: 10.1021/jm401276h BindingDB Entry DOI: 10.7270/Q2Q81H2C
					More data for this Ligand-Target Pair