null
SMILES: CC(C)c1nc(cc(=O)[nH]1)-c1ccncc1
InChI Key: InChIKey=JTCJGGGCNGPHSV-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM50494543![]() (CHEMBL3093037) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Mitsubishi Tanabe Pharma Corporation Curated by ChEMBL | Assay Description Inhibition of human recombinant GSK3beta using prephosphorylated GS1 peptide as substrate after 1 hr by liquid scintillation spectrometry | Bioorg Med Chem Lett 23: 6928-32 (2013) Article DOI: 10.1016/j.bmcl.2013.09.021 BindingDB Entry DOI: 10.7270/Q2736TV7 | |||||||||||
More data for this Ligand-Target Pair |