Found 5 hits for monomerid = 50494687 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Carbonic anhydrase 14
(Homo sapiens (Human)) | BDBM50494687
(CHEMBL3092810)Show SMILES CC(C)CC(=O)OC[C@H]1O[C@H]([C@H](OC(=O)CC(C)C)[C@@H](OC(=O)CC(C)C)[C@H]1OC(=O)CC(C)C)n1cc(nn1)-c1cccc(c1)S(N)(=O)=O |r| Show InChI InChI=1S/C34H50N4O11S/c1-19(2)12-27(39)45-18-26-31(47-28(40)13-20(3)4)32(48-29(41)14-21(5)6)33(49-30(42)15-22(7)8)34(46-26)38-17-25(36-37-38)23-10-9-11-24(16-23)50(35,43)44/h9-11,16-17,19-22,26,31-34H,12-15,18H2,1-8H3,(H2,35,43,44)/t26-,31+,32+,33-,34-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description
Inhibition of human carbonic anhydrase 14 by stopped-flow CO2 hydration assay |
J Med Chem 56: 9623-34 (2013)
Article DOI: 10.1021/jm401163e
BindingDB Entry DOI: 10.7270/Q2XK8JGS |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50494687
(CHEMBL3092810)Show SMILES CC(C)CC(=O)OC[C@H]1O[C@H]([C@H](OC(=O)CC(C)C)[C@@H](OC(=O)CC(C)C)[C@H]1OC(=O)CC(C)C)n1cc(nn1)-c1cccc(c1)S(N)(=O)=O |r| Show InChI InChI=1S/C34H50N4O11S/c1-19(2)12-27(39)45-18-26-31(47-28(40)13-20(3)4)32(48-29(41)14-21(5)6)33(49-30(42)15-22(7)8)34(46-26)38-17-25(36-37-38)23-10-9-11-24(16-23)50(35,43)44/h9-11,16-17,19-22,26,31-34H,12-15,18H2,1-8H3,(H2,35,43,44)/t26-,31+,32+,33-,34-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description
Inhibition of human carbonic anhydrase 12 by stopped-flow CO2 hydration assay |
J Med Chem 56: 9623-34 (2013)
Article DOI: 10.1021/jm401163e
BindingDB Entry DOI: 10.7270/Q2XK8JGS |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50494687
(CHEMBL3092810)Show SMILES CC(C)CC(=O)OC[C@H]1O[C@H]([C@H](OC(=O)CC(C)C)[C@@H](OC(=O)CC(C)C)[C@H]1OC(=O)CC(C)C)n1cc(nn1)-c1cccc(c1)S(N)(=O)=O |r| Show InChI InChI=1S/C34H50N4O11S/c1-19(2)12-27(39)45-18-26-31(47-28(40)13-20(3)4)32(48-29(41)14-21(5)6)33(49-30(42)15-22(7)8)34(46-26)38-17-25(36-37-38)23-10-9-11-24(16-23)50(35,43)44/h9-11,16-17,19-22,26,31-34H,12-15,18H2,1-8H3,(H2,35,43,44)/t26-,31+,32+,33-,34-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 254 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description
Inhibition of human carbonic anhydrase 9 by stopped-flow CO2 hydration assay |
J Med Chem 56: 9623-34 (2013)
Article DOI: 10.1021/jm401163e
BindingDB Entry DOI: 10.7270/Q2XK8JGS |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50494687
(CHEMBL3092810)Show SMILES CC(C)CC(=O)OC[C@H]1O[C@H]([C@H](OC(=O)CC(C)C)[C@@H](OC(=O)CC(C)C)[C@H]1OC(=O)CC(C)C)n1cc(nn1)-c1cccc(c1)S(N)(=O)=O |r| Show InChI InChI=1S/C34H50N4O11S/c1-19(2)12-27(39)45-18-26-31(47-28(40)13-20(3)4)32(48-29(41)14-21(5)6)33(49-30(42)15-22(7)8)34(46-26)38-17-25(36-37-38)23-10-9-11-24(16-23)50(35,43)44/h9-11,16-17,19-22,26,31-34H,12-15,18H2,1-8H3,(H2,35,43,44)/t26-,31+,32+,33-,34-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 1.88E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description
Inhibition of human carbonic anhydrase 1 by stopped-flow CO2 hydration assay |
J Med Chem 56: 9623-34 (2013)
Article DOI: 10.1021/jm401163e
BindingDB Entry DOI: 10.7270/Q2XK8JGS |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50494687
(CHEMBL3092810)Show SMILES CC(C)CC(=O)OC[C@H]1O[C@H]([C@H](OC(=O)CC(C)C)[C@@H](OC(=O)CC(C)C)[C@H]1OC(=O)CC(C)C)n1cc(nn1)-c1cccc(c1)S(N)(=O)=O |r| Show InChI InChI=1S/C34H50N4O11S/c1-19(2)12-27(39)45-18-26-31(47-28(40)13-20(3)4)32(48-29(41)14-21(5)6)33(49-30(42)15-22(7)8)34(46-26)38-17-25(36-37-38)23-10-9-11-24(16-23)50(35,43)44/h9-11,16-17,19-22,26,31-34H,12-15,18H2,1-8H3,(H2,35,43,44)/t26-,31+,32+,33-,34-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 4.78E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description
Inhibition of human carbonic anhydrase 2 by stopped-flow CO2 hydration assay |
J Med Chem 56: 9623-34 (2013)
Article DOI: 10.1021/jm401163e
BindingDB Entry DOI: 10.7270/Q2XK8JGS |
More data for this
Ligand-Target Pair | |
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