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SMILES: OCc1cccc(c1)-c1nc(N2CCOCC2)c2ncccc2n1

InChI Key: InChIKey=XXWFFCFOQNPIOZ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50495514   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50495514 (CHEMBL3109126) Show SMILES OCc1cccc(c1)-c1nc(N2CCOCC2)c2ncccc2n1 Show InChI InChI=1S/C18H18N4O2/c23-12-13-3-1-4-14(11-13)17-20-15-5-2-6-19-16(15)18(21-17)22-7-9-24-10-8-22/h1-6,11,23H,7-10,12H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	336	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of mTOR (unknown origin) after 2 hrs by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50495514 (CHEMBL3109126) Show SMILES OCc1cccc(c1)-c1nc(N2CCOCC2)c2ncccc2n1 Show InChI InChI=1S/C18H18N4O2/c23-12-13-3-1-4-14(11-13)17-20-15-5-2-6-19-16(15)18(21-17)22-7-9-24-10-8-22/h1-6,11,23H,7-10,12H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	183	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50495514 (CHEMBL3109126) Show SMILES OCc1cccc(c1)-c1nc(N2CCOCC2)c2ncccc2n1 Show InChI InChI=1S/C18H18N4O2/c23-12-13-3-1-4-14(11-13)17-20-15-5-2-6-19-16(15)18(21-17)22-7-9-24-10-8-22/h1-6,11,23H,7-10,12H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50495514 (CHEMBL3109126) Show SMILES OCc1cccc(c1)-c1nc(N2CCOCC2)c2ncccc2n1 Show InChI InChI=1S/C18H18N4O2/c23-12-13-3-1-4-14(11-13)17-20-15-5-2-6-19-16(15)18(21-17)22-7-9-24-10-8-22/h1-6,11,23H,7-10,12H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair