BDBM50495955 CHEMBL3121493

SMILES: Nc1ccn([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@]22CCCO2)c(=O)n1

InChI Key: InChIKey=RYPTYZUODKSHPB-UGKPPGOTSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50495955   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RNA-directed RNA polymerase (Hepacivirus C)	BDBM50495955 (CHEMBL3121493) Show SMILES Nc1ccn([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@]22CCCO2)c(=O)n1 |r| Show InChI InChI=1S/C12H20N3O14P3/c13-8-2-4-15(11(17)14-8)10-12(3-1-5-25-12)9(16)7(27-10)6-26-31(21,22)29-32(23,24)28-30(18,19)20/h2,4,7,9-10,16H,1,3,5-6H2,(H,21,22)(H,23,24)(H2,13,14,17)(H2,18,19,20)/t7-,9-,10-,12-/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pharmasset, Inc. Curated by ChEMBL					Assay Description Inhibition of HCV genotype 1b recombinant NS5B RNA dependent RNA polymerase S282T mutant using IRES RNA as substrate after 30 mins by radioactive ass...				J Med Chem 57: 1826-35 (2014) Article DOI: 10.1021/jm401224y BindingDB Entry DOI: 10.7270/Q2JQ140V
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