BDBM50495959 CHEMBL3121667

SMILES: Fc1ccccc1-c1nc2ccn(Cc3cc(no3)-c3ccc(cc3C(F)(F)F)C(F)(F)F)cc2n1

InChI Key: InChIKey=ORVJNZUEMUKFGW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50495959   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
1,3-beta-glucan synthase component GLS2 (Saccharomyces cerevisiae)	BDBM50495959 (CHEMBL3121667) Show SMILES Fc1ccccc1-c1nc2ccn(Cc3cc(no3)-c3ccc(cc3C(F)(F)F)C(F)(F)F)cc2n1 Show InChI InChI=1S/C24H13F7N4O/c25-18-4-2-1-3-16(18)22-32-19-7-8-35(12-21(19)33-22)11-14-10-20(34-36-14)15-6-5-13(23(26,27)28)9-17(15)24(29,30)31/h1-10,12H,11H2	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	794	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research & Development Curated by ChEMBL					Assay Description Inhibition of human ERG expressed in CHO cells				J Med Chem 57: 1964-75 (2014) Article DOI: 10.1021/jm401337x BindingDB Entry DOI: 10.7270/Q2DZ0C9K
					More data for this Ligand-Target Pair