BDBM50496201 CHEMBL3124983

SMILES: Nc1ncc(nc1-c1ccc(cc1)C(F)(F)F)-c1ccc(cc1)C(=O)N1CCOCC1

InChI Key: InChIKey=JTVQYNCQTWIEOM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50496201   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
1,3-beta-glucan synthase component GLS2 (Saccharomyces cerevisiae)	BDBM50496201 (CHEMBL3124983) Show SMILES Nc1ncc(nc1-c1ccc(cc1)C(F)(F)F)-c1ccc(cc1)C(=O)N1CCOCC1 Show InChI InChI=1S/C22H19F3N4O2/c23-22(24,25)17-7-5-15(6-8-17)19-20(26)27-13-18(28-19)14-1-3-16(4-2-14)21(30)29-9-11-31-12-10-29/h1-8,13H,9-12H2,(H2,26,27)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Cape Town Curated by ChEMBL					Assay Description Inhibition of human ERG by patch clamp electrophysiology				J Med Chem 56: 8860-71 (2013) Article DOI: 10.1021/jm401278d BindingDB Entry DOI: 10.7270/Q2GT5R5G
					More data for this Ligand-Target Pair