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SMILES: Cc1sc2nc(SCC(=O)Nc3cccc(c3)C(O)=O)nc(O)c2c1C

InChI Key: InChIKey=ORANHBYVJOBPJF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50497497   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50497497 (CHEMBL1572180) Show SMILES Cc1sc2nc(SCC(=O)Nc3cccc(c3)C(O)=O)nc(O)c2c1C Show InChI InChI=1S/C17H15N3O4S2/c1-8-9(2)26-15-13(8)14(22)19-17(20-15)25-7-12(21)18-11-5-3-4-10(6-11)16(23)24/h3-6H,7H2,1-2H3,(H,18,21)(H,23,24)(H,19,20,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology & Science-Pilani Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus DNA gyrase-mediated supercoiling of relaxed DNA using pBR 322 as substrate by agarose gel electrophoresis analysi...				Bioorg Med Chem 22: 5970-87 (2014) Article DOI: 10.1016/j.bmc.2014.09.008 BindingDB Entry DOI: 10.7270/Q23X89MP
					More data for this Ligand-Target Pair
DNA gyrase subunit B (Staphylococcus aureus)	BDBM50497497 (CHEMBL1572180) Show SMILES Cc1sc2nc(SCC(=O)Nc3cccc(c3)C(O)=O)nc(O)c2c1C Show InChI InChI=1S/C17H15N3O4S2/c1-8-9(2)26-15-13(8)14(22)19-17(20-15)25-7-12(21)18-11-5-3-4-10(6-11)16(23)24/h3-6H,7H2,1-2H3,(H,18,21)(H,23,24)(H,19,20,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.73E+4	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology & Science-Pilani Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus DNA gyrase B ATPase activity				Bioorg Med Chem 22: 5970-87 (2014) Article DOI: 10.1016/j.bmc.2014.09.008 BindingDB Entry DOI: 10.7270/Q23X89MP
					More data for this Ligand-Target Pair