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BDBM50499726 CHEMBL3742181

SMILES: Fc1ccc(Br)c(c1)C(=O)c1ccc(OCC(=O)Nc2cccnc2)cc1

InChI Key: InChIKey=ZUIZBOPGEGXBIA-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50499726   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
1,3-beta-glucan synthase component GLS2


(Saccharomyces cerevisiae)		BDBM50499726
PNG
(CHEMBL3742181)
Show SMILES Fc1ccc(Br)c(c1)C(=O)c1ccc(OCC(=O)Nc2cccnc2)cc1
Show InChI InChI=1S/C20H14BrFN2O3/c21-18-8-5-14(22)10-17(18)20(26)13-3-6-16(7-4-13)27-12-19(25)24-15-2-1-9-23-11-15/h1-11H,12H2,(H,24,25)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 4.60E+3n/an/an/an/a



Leiden University

Curated by ChEMBL


Assay Description
Induction of dissociation of [3H]-dofetilide from Kv11.1 channel (unknown origin) assessed as dissociation rate expressed in HEK293 cells after 1 hr

Eur J Med Chem 106: 50-9 (2015)


Article DOI: 10.1016/j.ejmech.2015.10.032
BindingDB Entry DOI: 10.7270/Q25X2CZB
More data for this
Ligand-Target Pair