BDBM50500140 CHEMBL3103854

SMILES: COc1cccc2C(=O)C3=C([C@@H](C)O[C@@H](Cn4cc(nn4)-c4ccccc4)C3)C(=O)c12

InChI Key: InChIKey=RHGXPWJMJQUARQ-GDBMZVCRSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50500140   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Indoleamine 2,3-dioxygenase (Homo sapiens (Human))	BDBM50500140 (CHEMBL3103854) Show SMILES COc1cccc2C(=O)C3=C([C@@H](C)O[C@@H](Cn4cc(nn4)-c4ccccc4)C3)C(=O)c12 |r,t:9| Show InChI InChI=1S/C24H21N3O4/c1-14-21-18(23(28)17-9-6-10-20(30-2)22(17)24(21)29)11-16(31-14)12-27-13-19(25-26-27)15-7-4-3-5-8-15/h3-10,13-14,16H,11-12H2,1-2H3/t14-,16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
SIB Swiss Institute of Bioinformatics Curated by ChEMBL					Assay Description Inhibition of 6His-tagged human recombinant IDO1 expressed in Escherichia coli EC 539 using L-tryptophan as substrate after 1 hr by plate reader anal...				J Med Chem 58: 9421-37 (2015) Article DOI: 10.1021/acs.jmedchem.5b00326 BindingDB Entry DOI: 10.7270/Q28K7D3X
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