BDBM50500151 CHEMBL3746386

SMILES: OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CCC(=O)NCCNC(=O)\N=C(\N)NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1

InChI Key: InChIKey=XIMBZVXBNYSXHR-KFSCGDPASA-N

Data: 9 KI  9 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50500151   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50500151 (CHEMBL3746386) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CCC(=O)NCCNC(=O)\N=C(\N)NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1 |r| Show InChI InChI=1S/C33H41N7O5.2C2HF3O2/c1-2-28(42)35-20-21-37-33(45)40-32(34)36-19-9-14-27(30(43)38-22-23-15-17-26(41)18-16-23)39-31(44)29(24-10-5-3-6-11-24)25-12-7-4-8-13-25;2*3-2(4,5)1(6)7/h3-8,10-13,15-18,27,29,41H,2,9,14,19-22H2,1H3,(H,35,42)(H,38,43)(H,39,44)(H4,34,36,37,40,45);2*(H,6,7)/t27-;;/m1../s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.0770	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS/IPBS (Institut de Pharmacologie et Biologie Structurale) Curated by ChEMBL					Assay Description Displacement of (R)-Na-Diphenylacetyl-Nomega[2-([2,3-3H]-propionylamino)ethyl]aminocarbonyl (4-hydroxybenzyl)-argininamide from NPY1R in human SK-N-M...				J Med Chem 58: 8834-49 (2015) Article DOI: 10.1021/acs.jmedchem.5b00925 BindingDB Entry DOI: 10.7270/Q2RN3BVG
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50500151 (CHEMBL3746386) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CCC(=O)NCCNC(=O)\N=C(\N)NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1 |r| Show InChI InChI=1S/C33H41N7O5.2C2HF3O2/c1-2-28(42)35-20-21-37-33(45)40-32(34)36-19-9-14-27(30(43)38-22-23-15-17-26(41)18-16-23)39-31(44)29(24-10-5-3-6-11-24)25-12-7-4-8-13-25;2*3-2(4,5)1(6)7/h3-8,10-13,15-18,27,29,41H,2,9,14,19-22H2,1H3,(H,35,42)(H,38,43)(H,39,44)(H4,34,36,37,40,45);2*(H,6,7)/t27-;;/m1../s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS/IPBS (Institut de Pharmacologie et Biologie Structurale) Curated by ChEMBL					Assay Description Displacement of [3H]propionyl-pNPY from NPY1R in human HEL cells preincubated for 30 mins followed by radioligand addition at 60 to 90 mins by flow c...				J Med Chem 58: 8834-49 (2015) Article DOI: 10.1021/acs.jmedchem.5b00925 BindingDB Entry DOI: 10.7270/Q2RN3BVG
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50500151 (CHEMBL3746386) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CCC(=O)NCCNC(=O)\N=C(\N)NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1 |r| Show InChI InChI=1S/C33H41N7O5.2C2HF3O2/c1-2-28(42)35-20-21-37-33(45)40-32(34)36-19-9-14-27(30(43)38-22-23-15-17-26(41)18-16-23)39-31(44)29(24-10-5-3-6-11-24)25-12-7-4-8-13-25;2*3-2(4,5)1(6)7/h3-8,10-13,15-18,27,29,41H,2,9,14,19-22H2,1H3,(H,35,42)(H,38,43)(H,39,44)(H4,34,36,37,40,45);2*(H,6,7)/t27-;;/m1../s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS/IPBS (Institut de Pharmacologie et Biologie Structurale) Curated by ChEMBL					Assay Description Displacement of [3H]propionyl-pNPY from NPY1R in human SK-N-MC cells compound treated immediately post radioligand treatment measured after 2 hrs by ...				J Med Chem 58: 8834-49 (2015) Article DOI: 10.1021/acs.jmedchem.5b00925 BindingDB Entry DOI: 10.7270/Q2RN3BVG
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50500151 (CHEMBL3746386) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CCC(=O)NCCNC(=O)\N=C(\N)NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1 |r| Show InChI InChI=1S/C33H41N7O5.2C2HF3O2/c1-2-28(42)35-20-21-37-33(45)40-32(34)36-19-9-14-27(30(43)38-22-23-15-17-26(41)18-16-23)39-31(44)29(24-10-5-3-6-11-24)25-12-7-4-8-13-25;2*3-2(4,5)1(6)7/h3-8,10-13,15-18,27,29,41H,2,9,14,19-22H2,1H3,(H,35,42)(H,38,43)(H,39,44)(H4,34,36,37,40,45);2*(H,6,7)/t27-;;/m1../s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS/IPBS (Institut de Pharmacologie et Biologie Structurale) Curated by ChEMBL					Assay Description Displacement of [3H]UR-MK136 from NPY1R in human SK-N-MC cells by radioligand binding assay				J Med Chem 58: 8834-49 (2015) Article DOI: 10.1021/acs.jmedchem.5b00925 BindingDB Entry DOI: 10.7270/Q2RN3BVG
					More data for this Ligand-Target Pair
Neuropeptide FF receptor 1 (Homo sapiens (Human))	BDBM50500151 (CHEMBL3746386) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CCC(=O)NCCNC(=O)\N=C(\N)NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1 |r| Show InChI InChI=1S/C33H41N7O5.2C2HF3O2/c1-2-28(42)35-20-21-37-33(45)40-32(34)36-19-9-14-27(30(43)38-22-23-15-17-26(41)18-16-23)39-31(44)29(24-10-5-3-6-11-24)25-12-7-4-8-13-25;2*3-2(4,5)1(6)7/h3-8,10-13,15-18,27,29,41H,2,9,14,19-22H2,1H3,(H,35,42)(H,38,43)(H,39,44)(H4,34,36,37,40,45);2*(H,6,7)/t27-;;/m1../s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS/IPBS (Institut de Pharmacologie et Biologie Structurale) Curated by ChEMBL					Assay Description Displacement of [3H]NPVF from human NPFF1 expressed in CHO cells by radioligand binding assay				J Med Chem 58: 8834-49 (2015) Article DOI: 10.1021/acs.jmedchem.5b00925 BindingDB Entry DOI: 10.7270/Q2RN3BVG
					More data for this Ligand-Target Pair
Neuropeptide FF receptor 2 (Homo sapiens (Human))	BDBM50500151 (CHEMBL3746386) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CCC(=O)NCCNC(=O)\N=C(\N)NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1 |r| Show InChI InChI=1S/C33H41N7O5.2C2HF3O2/c1-2-28(42)35-20-21-37-33(45)40-32(34)36-19-9-14-27(30(43)38-22-23-15-17-26(41)18-16-23)39-31(44)29(24-10-5-3-6-11-24)25-12-7-4-8-13-25;2*3-2(4,5)1(6)7/h3-8,10-13,15-18,27,29,41H,2,9,14,19-22H2,1H3,(H,35,42)(H,38,43)(H,39,44)(H4,34,36,37,40,45);2*(H,6,7)/t27-;;/m1../s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS/IPBS (Institut de Pharmacologie et Biologie Structurale) Curated by ChEMBL					Assay Description Displacement of [3H]EYF from human NPFF2 expressed in CHO cells by radioligand binding assay				J Med Chem 58: 8834-49 (2015) Article DOI: 10.1021/acs.jmedchem.5b00925 BindingDB Entry DOI: 10.7270/Q2RN3BVG
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 2 (Homo sapiens (Human))	BDBM50500151 (CHEMBL3746386) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CCC(=O)NCCNC(=O)\N=C(\N)NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1 |r| Show InChI InChI=1S/C33H41N7O5.2C2HF3O2/c1-2-28(42)35-20-21-37-33(45)40-32(34)36-19-9-14-27(30(43)38-22-23-15-17-26(41)18-16-23)39-31(44)29(24-10-5-3-6-11-24)25-12-7-4-8-13-25;2*3-2(4,5)1(6)7/h3-8,10-13,15-18,27,29,41H,2,9,14,19-22H2,1H3,(H,35,42)(H,38,43)(H,39,44)(H4,34,36,37,40,45);2*(H,6,7)/t27-;;/m1../s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS/IPBS (Institut de Pharmacologie et Biologie Structurale) Curated by ChEMBL					Assay Description Displacement of Cy5-pNPY from human NPY2R expressed in CHO cells by flow cytometric analysis				J Med Chem 58: 8834-49 (2015) Article DOI: 10.1021/acs.jmedchem.5b00925 BindingDB Entry DOI: 10.7270/Q2RN3BVG
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50500151 (CHEMBL3746386) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CCC(=O)NCCNC(=O)\N=C(\N)NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1 |r| Show InChI InChI=1S/C33H41N7O5.2C2HF3O2/c1-2-28(42)35-20-21-37-33(45)40-32(34)36-19-9-14-27(30(43)38-22-23-15-17-26(41)18-16-23)39-31(44)29(24-10-5-3-6-11-24)25-12-7-4-8-13-25;2*3-2(4,5)1(6)7/h3-8,10-13,15-18,27,29,41H,2,9,14,19-22H2,1H3,(H,35,42)(H,38,43)(H,39,44)(H4,34,36,37,40,45);2*(H,6,7)/t27-;;/m1../s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS/IPBS (Institut de Pharmacologie et Biologie Structurale) Curated by ChEMBL					Assay Description Displacement of Cy5-pNPY from human NPY5R expressed in HEC cells by flow cytometric analysis				J Med Chem 58: 8834-49 (2015) Article DOI: 10.1021/acs.jmedchem.5b00925 BindingDB Entry DOI: 10.7270/Q2RN3BVG
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50500151 (CHEMBL3746386) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CCC(=O)NCCNC(=O)\N=C(\N)NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1 |r| Show InChI InChI=1S/C33H41N7O5.2C2HF3O2/c1-2-28(42)35-20-21-37-33(45)40-32(34)36-19-9-14-27(30(43)38-22-23-15-17-26(41)18-16-23)39-31(44)29(24-10-5-3-6-11-24)25-12-7-4-8-13-25;2*3-2(4,5)1(6)7/h3-8,10-13,15-18,27,29,41H,2,9,14,19-22H2,1H3,(H,35,42)(H,38,43)(H,39,44)(H4,34,36,37,40,45);2*(H,6,7)/t27-;;/m1../s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS/IPBS (Institut de Pharmacologie et Biologie Structurale) Curated by ChEMBL					Assay Description Displacement of Cy5-[K4]hPP from human NPY4R expressed in CHO cells by flow cytometric analysis				J Med Chem 58: 8834-49 (2015) Article DOI: 10.1021/acs.jmedchem.5b00925 BindingDB Entry DOI: 10.7270/Q2RN3BVG
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50500151 (CHEMBL3746386) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CCC(=O)NCCNC(=O)\N=C(\N)NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1 |r| Show InChI InChI=1S/C33H41N7O5.2C2HF3O2/c1-2-28(42)35-20-21-37-33(45)40-32(34)36-19-9-14-27(30(43)38-22-23-15-17-26(41)18-16-23)39-31(44)29(24-10-5-3-6-11-24)25-12-7-4-8-13-25;2*3-2(4,5)1(6)7/h3-8,10-13,15-18,27,29,41H,2,9,14,19-22H2,1H3,(H,35,42)(H,38,43)(H,39,44)(H4,34,36,37,40,45);2*(H,6,7)/t27-;;/m1../s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
CNRS/IPBS (Institut de Pharmacologie et Biologie Structurale) Curated by ChEMBL					Assay Description Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 30 mins by Fura-2 dye bas...				J Med Chem 58: 8834-49 (2015) Article DOI: 10.1021/acs.jmedchem.5b00925 BindingDB Entry DOI: 10.7270/Q2RN3BVG
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50500151 (CHEMBL3746386) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CCC(=O)NCCNC(=O)\N=C(\N)NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1 |r| Show InChI InChI=1S/C33H41N7O5.2C2HF3O2/c1-2-28(42)35-20-21-37-33(45)40-32(34)36-19-9-14-27(30(43)38-22-23-15-17-26(41)18-16-23)39-31(44)29(24-10-5-3-6-11-24)25-12-7-4-8-13-25;2*3-2(4,5)1(6)7/h3-8,10-13,15-18,27,29,41H,2,9,14,19-22H2,1H3,(H,35,42)(H,38,43)(H,39,44)(H4,34,36,37,40,45);2*(H,6,7)/t27-;;/m1../s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.60	n/a	n/a	n/a	n/a	n/a	n/a
CNRS/IPBS (Institut de Pharmacologie et Biologie Structurale) Curated by ChEMBL					Assay Description Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 300 nM pNPY-induced Ca+2 response preincubated for 15 mins by Fura-2 dye ba...				J Med Chem 58: 8834-49 (2015) Article DOI: 10.1021/acs.jmedchem.5b00925 BindingDB Entry DOI: 10.7270/Q2RN3BVG
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50500151 (CHEMBL3746386) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CCC(=O)NCCNC(=O)\N=C(\N)NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1 |r| Show InChI InChI=1S/C33H41N7O5.2C2HF3O2/c1-2-28(42)35-20-21-37-33(45)40-32(34)36-19-9-14-27(30(43)38-22-23-15-17-26(41)18-16-23)39-31(44)29(24-10-5-3-6-11-24)25-12-7-4-8-13-25;2*3-2(4,5)1(6)7/h3-8,10-13,15-18,27,29,41H,2,9,14,19-22H2,1H3,(H,35,42)(H,38,43)(H,39,44)(H4,34,36,37,40,45);2*(H,6,7)/t27-;;/m1../s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.129	n/a	n/a	n/a	n/a	n/a	n/a
CNRS/IPBS (Institut de Pharmacologie et Biologie Structurale) Curated by ChEMBL					Assay Description Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 20 mins by Fura-2 dye bas...				J Med Chem 58: 8834-49 (2015) Article DOI: 10.1021/acs.jmedchem.5b00925 BindingDB Entry DOI: 10.7270/Q2RN3BVG
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50500151 (CHEMBL3746386) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CCC(=O)NCCNC(=O)\N=C(\N)NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1 |r| Show InChI InChI=1S/C33H41N7O5.2C2HF3O2/c1-2-28(42)35-20-21-37-33(45)40-32(34)36-19-9-14-27(30(43)38-22-23-15-17-26(41)18-16-23)39-31(44)29(24-10-5-3-6-11-24)25-12-7-4-8-13-25;2*3-2(4,5)1(6)7/h3-8,10-13,15-18,27,29,41H,2,9,14,19-22H2,1H3,(H,35,42)(H,38,43)(H,39,44)(H4,34,36,37,40,45);2*(H,6,7)/t27-;;/m1../s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.871	n/a	n/a	n/a	n/a	n/a	n/a
CNRS/IPBS (Institut de Pharmacologie et Biologie Structurale) Curated by ChEMBL					Assay Description Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 1 min by Fura-2 dye based...				J Med Chem 58: 8834-49 (2015) Article DOI: 10.1021/acs.jmedchem.5b00925 BindingDB Entry DOI: 10.7270/Q2RN3BVG
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50500151 (CHEMBL3746386) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CCC(=O)NCCNC(=O)\N=C(\N)NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1 |r| Show InChI InChI=1S/C33H41N7O5.2C2HF3O2/c1-2-28(42)35-20-21-37-33(45)40-32(34)36-19-9-14-27(30(43)38-22-23-15-17-26(41)18-16-23)39-31(44)29(24-10-5-3-6-11-24)25-12-7-4-8-13-25;2*3-2(4,5)1(6)7/h3-8,10-13,15-18,27,29,41H,2,9,14,19-22H2,1H3,(H,35,42)(H,38,43)(H,39,44)(H4,34,36,37,40,45);2*(H,6,7)/t27-;;/m1../s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.324	n/a	n/a	n/a	n/a	n/a	n/a
CNRS/IPBS (Institut de Pharmacologie et Biologie Structurale) Curated by ChEMBL					Assay Description Displacement of (R)-Na-Diphenylacetyl-Nomega[2-([2,3-3H]-propionylamino)ethyl]aminocarbonyl (4-hydroxybenzyl)-argininamide from NPY1R in human SK-N-M...				J Med Chem 58: 8834-49 (2015) Article DOI: 10.1021/acs.jmedchem.5b00925 BindingDB Entry DOI: 10.7270/Q2RN3BVG
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50500151 (CHEMBL3746386) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CCC(=O)NCCNC(=O)\N=C(\N)NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1 |r| Show InChI InChI=1S/C33H41N7O5.2C2HF3O2/c1-2-28(42)35-20-21-37-33(45)40-32(34)36-19-9-14-27(30(43)38-22-23-15-17-26(41)18-16-23)39-31(44)29(24-10-5-3-6-11-24)25-12-7-4-8-13-25;2*3-2(4,5)1(6)7/h3-8,10-13,15-18,27,29,41H,2,9,14,19-22H2,1H3,(H,35,42)(H,38,43)(H,39,44)(H4,34,36,37,40,45);2*(H,6,7)/t27-;;/m1../s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
CNRS/IPBS (Institut de Pharmacologie et Biologie Structurale) Curated by ChEMBL					Assay Description Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 10 secs by Fura-2 dye bas...				J Med Chem 58: 8834-49 (2015) Article DOI: 10.1021/acs.jmedchem.5b00925 BindingDB Entry DOI: 10.7270/Q2RN3BVG
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50500151 (CHEMBL3746386) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CCC(=O)NCCNC(=O)\N=C(\N)NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1 |r| Show InChI InChI=1S/C33H41N7O5.2C2HF3O2/c1-2-28(42)35-20-21-37-33(45)40-32(34)36-19-9-14-27(30(43)38-22-23-15-17-26(41)18-16-23)39-31(44)29(24-10-5-3-6-11-24)25-12-7-4-8-13-25;2*3-2(4,5)1(6)7/h3-8,10-13,15-18,27,29,41H,2,9,14,19-22H2,1H3,(H,35,42)(H,38,43)(H,39,44)(H4,34,36,37,40,45);2*(H,6,7)/t27-;;/m1../s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.417	n/a	n/a	n/a	n/a	n/a	n/a
CNRS/IPBS (Institut de Pharmacologie et Biologie Structurale) Curated by ChEMBL					Assay Description Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 2 mins by Fura-2 dye base...				J Med Chem 58: 8834-49 (2015) Article DOI: 10.1021/acs.jmedchem.5b00925 BindingDB Entry DOI: 10.7270/Q2RN3BVG
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50500151 (CHEMBL3746386) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CCC(=O)NCCNC(=O)\N=C(\N)NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1 |r| Show InChI InChI=1S/C33H41N7O5.2C2HF3O2/c1-2-28(42)35-20-21-37-33(45)40-32(34)36-19-9-14-27(30(43)38-22-23-15-17-26(41)18-16-23)39-31(44)29(24-10-5-3-6-11-24)25-12-7-4-8-13-25;2*3-2(4,5)1(6)7/h3-8,10-13,15-18,27,29,41H,2,9,14,19-22H2,1H3,(H,35,42)(H,38,43)(H,39,44)(H4,34,36,37,40,45);2*(H,6,7)/t27-;;/m1../s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.170	n/a	n/a	n/a	n/a	n/a	n/a
CNRS/IPBS (Institut de Pharmacologie et Biologie Structurale) Curated by ChEMBL					Assay Description Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 10 mins by Fura-2 dye bas...				J Med Chem 58: 8834-49 (2015) Article DOI: 10.1021/acs.jmedchem.5b00925 BindingDB Entry DOI: 10.7270/Q2RN3BVG
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50500151 (CHEMBL3746386) Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CCC(=O)NCCNC(=O)\N=C(\N)NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1 |r| Show InChI InChI=1S/C33H41N7O5.2C2HF3O2/c1-2-28(42)35-20-21-37-33(45)40-32(34)36-19-9-14-27(30(43)38-22-23-15-17-26(41)18-16-23)39-31(44)29(24-10-5-3-6-11-24)25-12-7-4-8-13-25;2*3-2(4,5)1(6)7/h3-8,10-13,15-18,27,29,41H,2,9,14,19-22H2,1H3,(H,35,42)(H,38,43)(H,39,44)(H4,34,36,37,40,45);2*(H,6,7)/t27-;;/m1../s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.170	n/a	n/a	n/a	n/a	n/a	n/a
CNRS/IPBS (Institut de Pharmacologie et Biologie Structurale) Curated by ChEMBL					Assay Description Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 5 mins by Fura-2 dye base...				J Med Chem 58: 8834-49 (2015) Article DOI: 10.1021/acs.jmedchem.5b00925 BindingDB Entry DOI: 10.7270/Q2RN3BVG
					More data for this Ligand-Target Pair