null

SMILES: [H][C@@]12CCN(C(=O)CC(C)(C)O)[C@]1([H])C(=O)N(C2)c1cccc2n(ncc12)-c1ccccc1F

InChI Key: InChIKey=VGPVZPALXCWXDX-NYHFZMIOSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50500959   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50500959 (CHEMBL3799939) Show SMILES [H][C@@]12CCN(C(=O)CC(C)(C)O)[C@]1([H])C(=O)N(C2)c1cccc2n(ncc12)-c1ccccc1F |r| Show InChI InChI=1S/C24H25FN4O3/c1-24(2,32)12-21(30)27-11-10-15-14-28(23(31)22(15)27)18-8-5-9-19-16(18)13-26-29(19)20-7-4-3-6-17(20)25/h3-9,13,15,22,32H,10-12,14H2,1-2H3/t15-,22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Curated by ChEMBL					Assay Description Inhibition of recombinant human Nav1.7 expressed in HEK293F cells preincubated for 40 mins followed by DiSBAC2 substrate addition measured after 90 m...				J Med Chem 59: 3373-91 (2016) Article DOI: 10.1021/acs.jmedchem.6b00063 BindingDB Entry DOI: 10.7270/Q2C250GW
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50500959 (CHEMBL3799939) Show SMILES [H][C@@]12CCN(C(=O)CC(C)(C)O)[C@]1([H])C(=O)N(C2)c1cccc2n(ncc12)-c1ccccc1F |r| Show InChI InChI=1S/C24H25FN4O3/c1-24(2,32)12-21(30)27-11-10-15-14-28(23(31)22(15)27)18-8-5-9-19-16(18)13-26-29(19)20-7-4-3-6-17(20)25/h3-9,13,15,22,32H,10-12,14H2,1-2H3/t15-,22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.64E+4	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Curated by ChEMBL					Assay Description Inhibition of human Nav1.5 expressed in HEK293 cells by whole cell-patch clamp method				J Med Chem 59: 3373-91 (2016) Article DOI: 10.1021/acs.jmedchem.6b00063 BindingDB Entry DOI: 10.7270/Q2C250GW
					More data for this Ligand-Target Pair