BDBM50502829 CHEMBL4586752

SMILES: FC(F)(F)[C@@H](N[C@@H](Cc1ccccc1)C(=O)N[C@H](Cc1ccccc1)C#N)c1ccccc1

InChI Key: InChIKey=YWDVJUYPASCVGI-SGNDLWITSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50502829   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Procathepsin L (Homo sapiens (Human))	BDBM50502829 (CHEMBL4586752) Show SMILES FC(F)(F)[C@@H](N[C@@H](Cc1ccccc1)C(=O)N[C@H](Cc1ccccc1)C#N)c1ccccc1 |r| Show InChI InChI=1S/C26H24F3N3O/c27-26(28,29)24(21-14-8-3-9-15-21)32-23(17-20-12-6-2-7-13-20)25(33)31-22(18-30)16-19-10-4-1-5-11-19/h1-15,22-24,32H,16-17H2,(H,31,33)/t22-,23+,24+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	631	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de S£o Paulo Curated by ChEMBL					Assay Description Inhibition of Cathepsin L (unknown origin) using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins followed by susbtrate additi...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115083
					More data for this Ligand-Target Pair
Cruzipain (Trypanosoma cruzi)	BDBM50502829 (CHEMBL4586752) Show SMILES FC(F)(F)[C@@H](N[C@@H](Cc1ccccc1)C(=O)N[C@H](Cc1ccccc1)C#N)c1ccccc1 |r| Show InChI InChI=1S/C26H24F3N3O/c27-26(28,29)24(21-14-8-3-9-15-21)32-23(17-20-12-6-2-7-13-20)25(33)31-22(18-30)16-19-10-4-1-5-11-19/h1-15,22-24,32H,16-17H2,(H,31,33)/t22-,23+,24+/m1/s1	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.51E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade de S£o Paulo Curated by ChEMBL					Assay Description Inhibition of Trypanosoma cruzi cruzain using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins followed by susbtrate addition ...				Bioorg Med Chem 27: (2019) Article DOI: 10.1016/j.bmc.2019.115083
					More data for this Ligand-Target Pair