BDBM50503113 CHEMBL4516412

SMILES: [H][C@]12CCC[C@](N1CC(C)(C)F)(c1[nH]c3ccccc3c1C2)c1c(F)cc(OCCN2CC(CF)C2)cc1F

InChI Key: InChIKey=VDZDUPAUPFNMQF-PRAQEBQASA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50503113   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor (Homo sapiens (Human))	BDBM50503113 (CHEMBL4516412) Show SMILES [H][C@]12CCC[C@](N1CC(C)(C)F)(c1[nH]c3ccccc3c1C2)c1c(F)cc(OCCN2CC(CF)C2)cc1F |r,TLB:7:6:21.20.12:4.2.3| Show InChI InChI=1S/C30H35F4N3O/c1-29(2,34)18-37-20-6-5-9-30(37,28-23(12-20)22-7-3-4-8-26(22)35-28)27-24(32)13-21(14-25(27)33)38-11-10-36-16-19(15-31)17-36/h3-4,7-8,13-14,19-20,35H,5-6,9-12,15-18H2,1-2H3/t20-,30-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of fluorescent labelled fluormone ES2 from human recombinant GST tagged ER alpha LBD ( 282 to 595 residues) expressed in baculovirus inf...				ACS Med Chem Lett 10: 1492-1497 (2019) Article DOI: 10.1021/acsmedchemlett.9b00370
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50503113 (CHEMBL4516412) Show SMILES [H][C@]12CCC[C@](N1CC(C)(C)F)(c1[nH]c3ccccc3c1C2)c1c(F)cc(OCCN2CC(CF)C2)cc1F |r,TLB:7:6:21.20.12:4.2.3| Show InChI InChI=1S/C30H35F4N3O/c1-29(2,34)18-37-20-6-5-9-30(37,28-23(12-20)22-7-3-4-8-26(22)35-28)27-24(32)13-21(14-25(27)33)38-11-10-36-16-19(15-31)17-36/h3-4,7-8,13-14,19-20,35H,5-6,9-12,15-18H2,1-2H3/t20-,30-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Induction of ERalpha degradation in human MCF7 cells assessed as downregulation of ER alpha receptor expression measured after 18 to 22 hrs by immuno...				ACS Med Chem Lett 10: 1492-1497 (2019) Article DOI: 10.1021/acsmedchemlett.9b00370
					More data for this Ligand-Target Pair