BDBM50504656 CHEMBL1549549

SMILES: CN(C)C(=O)COc1ccc(cc1)C(=O)\C=C\c1cccnc1

InChI Key: InChIKey=ATCOJFWZWDWNDM-BJMVGYQFSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50504656   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear factor erythroid 2-related factor 2 (Homo sapiens (Human))	BDBM50504656 (CHEMBL1549549) Show SMILES CN(C)C(=O)COc1ccc(cc1)C(=O)\C=C\c1cccnc1 Show InChI InChI=1S/C18H18N2O3/c1-20(2)18(22)13-23-16-8-6-15(7-9-16)17(21)10-5-14-4-3-11-19-12-14/h3-12H,13H2,1-2H3/b10-5+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.46E+3	n/a	n/a	n/a	n/a
Korea Institute of Science and Technology (KIST) Curated by ChEMBL					Assay Description Activation of NRF2 in human U2OS cells co-expressing Keap1 (unknown origin) assessed as induction of NRF2 translocation to nucleus incubated for 6 hr...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111777
					More data for this Ligand-Target Pair