BDBM50508360 CHEMBL4437224

SMILES: COc1cccc(c1)-c1ccc(o1)C(=O)N1CCN(Cc2ccc(OC3CCNCC3)c(Cl)c2)CC1

InChI Key: InChIKey=LRXDFHYDWBBBKI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50508360   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urotensin II receptor (Homo sapiens (Human))	BDBM50508360 (CHEMBL4437224) Show SMILES COc1cccc(c1)-c1ccc(o1)C(=O)N1CCN(Cc2ccc(OC3CCNCC3)c(Cl)c2)CC1 Show InChI InChI=1S/C28H32ClN3O4/c1-34-23-4-2-3-21(18-23)25-7-8-27(36-25)28(33)32-15-13-31(14-16-32)19-20-5-6-26(24(29)17-20)35-22-9-11-30-12-10-22/h2-8,17-18,22,30H,9-16,19H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Displacement of Eu-labelled UT2 from recombinant human UT2 receptor expressed in HEK293 cell membranes preincubated for 10 mins followed by Eu-labell...				Bioorg Med Chem Lett 29: 577-580 (2019) Article DOI: 10.1016/j.bmcl.2018.12.058
					More data for this Ligand-Target Pair
Urotensin II receptor (Homo sapiens (Human))	BDBM50508360 (CHEMBL4437224) Show SMILES COc1cccc(c1)-c1ccc(o1)C(=O)N1CCN(Cc2ccc(OC3CCNCC3)c(Cl)c2)CC1 Show InChI InChI=1S/C28H32ClN3O4/c1-34-23-4-2-3-21(18-23)25-7-8-27(36-25)28(33)32-15-13-31(14-16-32)19-20-5-6-26(24(29)17-20)35-22-9-11-30-12-10-22/h2-8,17-18,22,30H,9-16,19H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Antagonist activity at human UT2 receptor expressed in HEK293-aeq cells assessed as inhibition of U2-induced intracellular calcium mobilization prein...				Bioorg Med Chem Lett 29: 577-580 (2019) Article DOI: 10.1016/j.bmcl.2018.12.058
					More data for this Ligand-Target Pair