BDBM50509011 CHEMBL4538713
SMILES: N[C@H](CN1C[C@H](CCCB(O)O)[C@@](N)(C1)C(O)=O)Cc1ccccc1
InChI Key: InChIKey=YNYVUJLGINQWRB-ZOBUZTSGSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Arginase-1 (Homo sapiens (Human)) | BDBM50509011 (CHEMBL4538713) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
New England Discovery Partners Curated by ChEMBL | Assay Description Inhibition of human recombinant arginase 1 expressed in Escherichia coli BL21 (DE3) assessed as reduction in urea production using L-arginine as subs... | J Med Chem 62: 8164-8177 (2019) Article DOI: 10.1021/acs.jmedchem.9b00931 | |||||||||||
More data for this Ligand-Target Pair |