BDBM50509521 CHEMBL4439970
SMILES: Cc1ccc(cc1NCc1cncc(c1)C(N)=O)C(=O)Nc1cccc(c1)C(F)(F)F
InChI Key: InChIKey=IPXKPFIHNPASKD-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Epithelial discoidin domain-containing receptor 1 (Homo sapiens (Human)) | BDBM50509521![]() (CHEMBL4439970) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Curated by ChEMBL | Assay Description Inhibition of kinase tracer 178 binding to recombinant human His-tagged DDR1 expressed in baculovirus infected Sf9 cells incubated for 1 hr by TR-FRE... | ACS Med Chem Lett 11: 29-33 (2020) Article DOI: 10.1021/acsmedchemlett.9b00382 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Discoidin domain-containing receptor 2 (Homo sapiens (Human)) | BDBM50509521![]() (CHEMBL4439970) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University Curated by ChEMBL | Assay Description Inhibition of kinase tracer 178 binding to recombinant human His-tagged DDR2 expressed in baculovirus infected Sf9 cells incubated for 1 hr by TR-FRE... | ACS Med Chem Lett 11: 29-33 (2020) Article DOI: 10.1021/acsmedchemlett.9b00382 | |||||||||||
More data for this Ligand-Target Pair |