BDBM50510099 CHEMBL4517895
SMILES: [#6]-[#8]-c1ccc(\[#6]=[#6]\c2c(-[#6]\[#6]=[#6](\[#6])-[#6])c(-[#8])cc3-[#8]C([#6])([#6])[#6]-[#6]-c23)cc1-[#8]
InChI Key: InChIKey=IYCGBIASDVDADJ-JXMROGBWSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin E synthase/G/H synthase 2 (Homo sapiens (Human)) | BDBM50510099 (CHEMBL4517895) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.55E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Czech Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of human recombinant COX2 assessed as reduction in PGE2 production using arachidonic acid substrate by ELISA | J Nat Prod 82: 1839-1848 (2019) Article DOI: 10.1021/acs.jnatprod.9b00081 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase (cyclooxygenase) (Ovis aries (Sheep)) | BDBM50510099 (CHEMBL4517895) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.26E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Czech Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of ram seminal vesicle COX1 assessed as reduction in PGE2 production using arachidonic acid substrate by ELISA | J Nat Prod 82: 1839-1848 (2019) Article DOI: 10.1021/acs.jnatprod.9b00081 | |||||||||||
More data for this Ligand-Target Pair |