Found 4 hits for monomerid = 505105 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Tyrosine-protein kinase JAK1 [574-1154]
(Homo sapiens (Human)) | BDBM505105
![PNG](/data/jpeg/tenK50/BindingDB_505105.png) (US11066406, B)Show SMILES OCc1nc2ccc3[nH]ccc3c2n1C1CCC(CC1)C#N |(-5.4,3.9,;-3.94,3.43,;-3.62,1.92,;-4.65,.77,;-3.88,-.56,;-4.35,-2.02,;-3.32,-3.17,;-1.82,-2.85,;-.57,-3.75,;.68,-2.85,;.2,-1.38,;-1.34,-1.38,;-2.37,-.24,;-2.21,1.29,;-.88,2.06,;-.88,3.6,;.46,4.37,;1.79,3.6,;1.79,2.06,;.46,1.29,;3.13,4.37,;3.13,5.91,)| | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| | n/a | n/a | <0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2571G4J |
More data for this Ligand-Target Pair | |
Non-receptor tyrosine-protein kinase TYK2 [580-1182]
(Homo sapiens (Human)) | BDBM505105
![PNG](/data/jpeg/tenK50/BindingDB_505105.png) (US11066406, B)Show SMILES OCc1nc2ccc3[nH]ccc3c2n1C1CCC(CC1)C#N |(-5.4,3.9,;-3.94,3.43,;-3.62,1.92,;-4.65,.77,;-3.88,-.56,;-4.35,-2.02,;-3.32,-3.17,;-1.82,-2.85,;-.57,-3.75,;.68,-2.85,;.2,-1.38,;-1.34,-1.38,;-2.37,-.24,;-2.21,1.29,;-.88,2.06,;-.88,3.6,;.46,4.37,;1.79,3.6,;1.79,2.06,;.46,1.29,;3.13,4.37,;3.13,5.91,)| | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| | n/a | n/a | <0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2571G4J |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase JAK3 [512-1124]
(Homo sapiens (Human)) | BDBM505105
![PNG](/data/jpeg/tenK50/BindingDB_505105.png) (US11066406, B)Show SMILES OCc1nc2ccc3[nH]ccc3c2n1C1CCC(CC1)C#N |(-5.4,3.9,;-3.94,3.43,;-3.62,1.92,;-4.65,.77,;-3.88,-.56,;-4.35,-2.02,;-3.32,-3.17,;-1.82,-2.85,;-.57,-3.75,;.68,-2.85,;.2,-1.38,;-1.34,-1.38,;-2.37,-.24,;-2.21,1.29,;-.88,2.06,;-.88,3.6,;.46,4.37,;1.79,3.6,;1.79,2.06,;.46,1.29,;3.13,4.37,;3.13,5.91,)| | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| | n/a | n/a | 13.4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2571G4J |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase JAK2 [532-1132]
(Homo sapiens (Human)) | BDBM505105
![PNG](/data/jpeg/tenK50/BindingDB_505105.png) (US11066406, B)Show SMILES OCc1nc2ccc3[nH]ccc3c2n1C1CCC(CC1)C#N |(-5.4,3.9,;-3.94,3.43,;-3.62,1.92,;-4.65,.77,;-3.88,-.56,;-4.35,-2.02,;-3.32,-3.17,;-1.82,-2.85,;-.57,-3.75,;.68,-2.85,;.2,-1.38,;-1.34,-1.38,;-2.37,-.24,;-2.21,1.29,;-.88,2.06,;-.88,3.6,;.46,4.37,;1.79,3.6,;1.79,2.06,;.46,1.29,;3.13,4.37,;3.13,5.91,)| | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| | n/a | n/a | <0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2571G4J |
More data for this Ligand-Target Pair | |