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BDBM50511263 CHEMBL4448689

SMILES: CC(=O)N1CCc2oc(=O)n(C(=O)NCCCCc3ccccc3)c2C1

InChI Key: InChIKey=IDWNECZAZXVXPG-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50511263   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Acid ceramidase


(Homo sapiens (Human))
BDBM50511263
PNG
(CHEMBL4448689)
Show SMILES CC(=O)N1CCc2oc(=O)n(C(=O)NCCCCc3ccccc3)c2C1
Show InChI InChI=1S/C19H23N3O4/c1-14(23)21-12-10-17-16(13-21)22(19(25)26-17)18(24)20-11-6-5-9-15-7-3-2-4-8-15/h2-4,7-8H,5-6,9-13H2,1H3,(H,20,24)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 293n/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
Inhibition of human acid ceramidase expressed in HEK293 cells using Rbm14-12 as substrate preincubated for 10 mins followed by substrate addition and...


J Med Chem 63: 3634-3664 (2020)


Article DOI: 10.1021/acs.jmedchem.9b02004
More data for this
Ligand-Target Pair