BDBM50512315 CHEMBL4438040

SMILES: Cl.[#8]-c1c(Cl)cc(-n2[se;v2]c3cccc(F)c3c2=O)c2cccnc12

InChI Key: InChIKey=GGJTYQYWXRMIAI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50512315   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta amyloid A4 protein (Homo sapiens (Human))	BDBM50512315 (CHEMBL4438040) Show SMILES Cl.[#8]-c1c(Cl)cc(-n2[se;v2]c3cccc(F)c3c2=O)c2cccnc12 Show InChI InChI=1S/C16H8ClFN2O2Se/c17-9-7-11(8-3-2-6-19-14(8)15(9)21)20-16(22)13-10(18)4-1-5-12(13)23-20/h1-7,21H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wuhan University of Technology Curated by ChEMBL					Assay Description Inhibition of amyloid beta (1 to 42) (unknown origin) aggregation				Eur J Med Chem 173: 117-153 (2019) Article DOI: 10.1016/j.ejmech.2019.03.063
					More data for this Ligand-Target Pair