null
SMILES: OC(=O)CC(Cc1ccc(OCCc2ccc3CCCNc3n2)cc1)c1ccccc1
InChI Key: InChIKey=DTLIDYQJLOBQPK-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Integrin alpha-V/beta-6 (Homo sapiens (Human)) | BDBM50513970 (CHEMBL4557585) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL | Assay Description Inhibition of recombinant human integrin alphaV (31 to 992 residues) beta6 (22 to 707 residues) expressed in CHO cells preincubated for 15 mins follo... | J Med Chem 62: 8796-8808 (2019) Article DOI: 10.1021/acs.jmedchem.9b00962 BindingDB Entry DOI: 10.7270/Q2WQ0752 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-V/beta-3 (Homo sapiens (Human)) | BDBM50513970 (CHEMBL4557585) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL | Assay Description Inhibition of recombinant human integrin alphaV (31 to 992 residues) beta3 (27 to 718 residues) expressed in CHO cells preincubated for 15 mins follo... | J Med Chem 62: 8796-8808 (2019) Article DOI: 10.1021/acs.jmedchem.9b00962 BindingDB Entry DOI: 10.7270/Q2WQ0752 | |||||||||||
More data for this Ligand-Target Pair |