null
SMILES: COc1cc2c(OC[C@@H]3CCC(=O)N3)ncc(Br)c2cc1C(N)=O
InChI Key: InChIKey=IPUGCJLTEYLCFC-QMMMGPOBSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Interleukin-1 receptor-associated kinase 1 (Homo sapiens (Human)) | BDBM50515374 (CHEMBL4536517) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL | Assay Description Binding affinity to human IRK1 using myelin basic protein as substrate by [gamma-33P]-ATP assay | ACS Med Chem Lett 10: 1081-1085 (2019) Article DOI: 10.1021/acsmedchemlett.9b00219 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 4 (Homo sapiens (Human)) | BDBM50515374 (CHEMBL4536517) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Medicines Research Centre Curated by ChEMBL | Assay Description Binding affinity to human IRK4 using myelin basic protein as substrate by [gamma-33P]-ATP assay | ACS Med Chem Lett 10: 1081-1085 (2019) Article DOI: 10.1021/acsmedchemlett.9b00219 | |||||||||||
More data for this Ligand-Target Pair |