BDBM50515602 CHEMBL4517386

SMILES: CC(=O)N(Cc1ccc(OCc2ccc(F)cc2)cc1)C(C(=O)NC1CCCCC1)c1c([nH]c2cc(Cl)ccc12)C(O)=O

InChI Key: InChIKey=GCYOJGNHSQSNLB-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50515602   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MDM2-MDMX (Homo sapiens (Human))	BDBM50515602 (CHEMBL4517386) Show SMILES CC(=O)N(Cc1ccc(OCc2ccc(F)cc2)cc1)C(C(=O)NC1CCCCC1)c1c([nH]c2cc(Cl)ccc12)C(O)=O Show InChI InChI=1S/C33H33ClFN3O5/c1-20(39)38(18-21-9-14-26(15-10-21)43-19-22-7-12-24(35)13-8-22)31(32(40)36-25-5-3-2-4-6-25)29-27-16-11-23(34)17-28(27)37-30(29)33(41)42/h7-17,25,31,37H,2-6,18-19H2,1H3,(H,36,40)(H,41,42)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.28E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Displacement of 5'FAM-LTFEHYWAQLTS from human recombinant N-terminal domain of MDM2 (1 to 118 residues) expressed in Escherichia coli BL21 (DE3) cell...				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111588
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