BDBM50515614 CHEMBL4453195

SMILES: CC(C)(C)NC(=O)C(N(Cc1ccc(OCc2c(Cl)cccc2Cl)cc1)C=O)c1c([nH]c2cc(Cl)ccc12)C(O)=O

InChI Key: InChIKey=BFRNRLIDPDCUSK-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50515614   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MDM2-MDMX (Homo sapiens (Human))	BDBM50515614 (CHEMBL4453195) Show SMILES CC(C)(C)NC(=O)C(N(Cc1ccc(OCc2c(Cl)cccc2Cl)cc1)C=O)c1c([nH]c2cc(Cl)ccc12)C(O)=O Show InChI InChI=1S/C30H28Cl3N3O5/c1-30(2,3)35-28(38)27(25-20-12-9-18(31)13-24(20)34-26(25)29(39)40)36(16-37)14-17-7-10-19(11-8-17)41-15-21-22(32)5-4-6-23(21)33/h4-13,16,27,34H,14-15H2,1-3H3,(H,35,38)(H,39,40)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.67E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Displacement of 5'FAM-LTFEHYWAQLTS from human recombinant N-terminal domain of MDM2 (1 to 118 residues) expressed in Escherichia coli BL21 (DE3) cell...				Eur J Med Chem 182: (2019) Article DOI: 10.1016/j.ejmech.2019.111588
					More data for this Ligand-Target Pair