null

SMILES: CN1CCN(CC1)c1nc(N)nc(COc2ccc(Cl)cc2Cl)n1

InChI Key: InChIKey=QPNBWEBABUOGBX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50516530   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50516530 (CHEMBL4473083) Show SMILES CN1CCN(CC1)c1nc(N)nc(COc2ccc(Cl)cc2Cl)n1 Show InChI InChI=1S/C15H18Cl2N6O/c1-22-4-6-23(7-5-22)15-20-13(19-14(18)21-15)9-24-12-3-2-10(16)8-11(12)17/h2-3,8H,4-7,9H2,1H3,(H2,18,19,20,21)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	128	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Displacement of [3H]-LSD from human 5-HT6R expressed in human HEK293 cells incubated for 1 hr by radioligand binding assay				Eur J Med Chem 178: 740-751 (2019) Article DOI: 10.1016/j.ejmech.2019.06.022
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50516530 (CHEMBL4473083) Show SMILES CN1CCN(CC1)c1nc(N)nc(COc2ccc(Cl)cc2Cl)n1 Show InChI InChI=1S/C15H18Cl2N6O/c1-22-4-6-23(7-5-22)15-20-13(19-14(18)21-15)9-24-12-3-2-10(16)8-11(12)17/h2-3,8H,4-7,9H2,1H3,(H2,18,19,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.23E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Displacement of [3H]-raclopride from human D2L receptor expressed in human HEK293 cells incubated for 1 hr by radioligand binding assay				Eur J Med Chem 178: 740-751 (2019) Article DOI: 10.1016/j.ejmech.2019.06.022
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50516530 (CHEMBL4473083) Show SMILES CN1CCN(CC1)c1nc(N)nc(COc2ccc(Cl)cc2Cl)n1 Show InChI InChI=1S/C15H18Cl2N6O/c1-22-4-6-23(7-5-22)15-20-13(19-14(18)21-15)9-24-12-3-2-10(16)8-11(12)17/h2-3,8H,4-7,9H2,1H3,(H2,18,19,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.61E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from human 5-HT1A expressed in human HEK293 cells assessed as inhibitory constant incubated for 1 hr by radioligand bi...				Eur J Med Chem 178: 740-751 (2019) Article DOI: 10.1016/j.ejmech.2019.06.022
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50516530 (CHEMBL4473083) Show SMILES CN1CCN(CC1)c1nc(N)nc(COc2ccc(Cl)cc2Cl)n1 Show InChI InChI=1S/C15H18Cl2N6O/c1-22-4-6-23(7-5-22)15-20-13(19-14(18)21-15)9-24-12-3-2-10(16)8-11(12)17/h2-3,8H,4-7,9H2,1H3,(H2,18,19,20,21)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from human 5-HT7R expressed in human HEK293 cells assessed as inhibitory constant incubated for 1 hr by radioligand binding...				Eur J Med Chem 178: 740-751 (2019) Article DOI: 10.1016/j.ejmech.2019.06.022
					More data for this Ligand-Target Pair